Epidemiology of community-acquired and recurrent Clostridioides difficile infection

Clostridioides difficile infection is a leading cause of healthcare-associated infections with significant morbidity and mortality. For the past decade, the bulk of infection prevention and epidemiologic surveillance efforts have been directed toward mitigating hospital-acquired C. difficile. Howeve...

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Bibliographic Details
Published in:Therapeutic Advances in Gastroenterology 2021, Vol.14, p.17562848211016248-17562848211016248
Main Authors: Fu, Yichun, Luo, Yuying, Grinspan, Ari M
Format: Article
Language:English
Subjects:
Clostridioides difficile Infection: Approaching a Difficult Menace
Epidemiology
Gastroenterology
Infections
Mortality
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Summary:Clostridioides difficile infection is a leading cause of healthcare-associated infections with significant morbidity and mortality. For the past decade, the bulk of infection prevention and epidemiologic surveillance efforts have been directed toward mitigating hospital-acquired C. difficile. However, the incidence of community-associated infection is on the rise. Patients with community-associated C. difficile tend to be younger and have lower mortality rate. Rates of recurrent C. difficile infection overall have decreased in the United States, but future research and public health endeavors are needed to standardize and improve disease detection, stratify risk factors in large-scale population studies, and to identify regional and local variations in strain types, reservoirs and transmission routes to help characterize and combat the changing epidemiology of C. difficile.
ISSN:1756-2848
1756-283X
1756-2848
DOI:10.1177/17562848211016248