Consanguinity, inbreeding coefficient, fertility and birth-outcome in population of Okara district, Pakistan

This study was aimed to illustrate the determents of consanguinity and inbreeding coefficient-F (ICF) in the population of Okara district of Pakistan and to elucidate the impact of consanguinity on fertility and birth outcome. Through a cross-sectional sampling design, 1,521 married women were recru...

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Bibliographic Details
Published in:Pakistan journal of medical sciences 2021-06, Vol.37 (3), p.770-775
Main Authors: Nawaz, Aqeela, Zaman, Muhammad, Malik, Sajid
Format: Article
Language:English
Subjects:
Age
Births
Demography
Epidemiology
Family structure
Fertility
Genetic disorders
Households
Illiteracy
Literacy
Marriage
Medical research
Medicine, Experimental
Mortality
Original
Pakistan
Population
Pregnancy
Variables
Womens health
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Summary:This study was aimed to illustrate the determents of consanguinity and inbreeding coefficient-F (ICF) in the population of Okara district of Pakistan and to elucidate the impact of consanguinity on fertility and birth outcome. Through a cross-sectional sampling design, 1,521 married women were recruited from Okara district during 2016-2017. Data on demographic variables, marital union types, subject's fertility, and reproductive outcome, were gathered in face-to-face interviews. Descriptive statistics and multivariable logistic regression were employed. The prevalence of consanguineous unions (CU) was calculated to be 61% yielding ICF=0.0356. Multivariable regression analyses revealed that six variables including younger age at marriage, joint family structure, caste-system of spouse, exchange marriage, matrimonial distance, and parental consanguinity, were significant predictors of consanguinity. The women having CU had significantly higher mean fertility, mean live-births and mean live-born sons compared with subjects having non-consanguineous unions (NCU). However, there were no significant differences in the average mortalities, i.e., prenatal, postnatal and
ISSN:1682-024X
1681-715X
DOI:10.12669/pjms.37.3.2263