Convalescent plasma as a treatment modality for Coronavirus Disease 2019 in Indonesia: A case reports

Coronavirus Disease 2019 (COVID-19) has become a pandemic since the beginning of 2020. COVID-19 is also spreading very rapidly in Indonesia and so far, no definitive therapy has been found. We report two cases of confirmed COVID-19 with moderate pneumonia, who received 400 ml of convalescent plasma...

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Bibliographic Details
Published in:Annals of medicine and surgery 2021-06, Vol.66, p.102444, Article 102444
Main Authors: Thabrani, Achmad, Hadi, Wahid Syamsul, Thobari, Jarir At, Novianti, Zakiah, Kurniyanto, Juliana, Indah, Suharto, Agus, Danaswari, Atik Nuriyah, Septiani, Ika, Rhatomy, Sholahuddin
Format: Article
Language:English
Subjects:
Adjunctive therapy treatment
Case Report
Convalescent plasma
COVID-19
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Summary:Coronavirus Disease 2019 (COVID-19) has become a pandemic since the beginning of 2020. COVID-19 is also spreading very rapidly in Indonesia and so far, no definitive therapy has been found. We report two cases of confirmed COVID-19 with moderate pneumonia, who received 400 ml of convalescent plasma and showed improvements in clinical, laboratory and radiological examinations. Passive immunotherapy is generally more effective when given early. Plasma transfusion is more beneficial when given before clinical conditions become severe. Some studies have shown that therapy with convalescent plasma can contribute to a longer survival and a lower length of stay. Convalescent plasma can be used as an adjunctive therapy option for patients with moderate COVID-19. •COVID-19.•Convalescent Plasma.•Alternative treatment.
ISSN:2049-0801
2049-0801
DOI:10.1016/j.amsu.2021.102444