Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections

Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-i...

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Bibliographic Details
Published in:Biophysical reviews 2021-06, Vol.13 (3), p.359-385
Main Authors: Lukose, Jijo, M., Sanoop Pavithran, N., Mithun, Barik, Ajaya Kumar, Pai, Keerthilatha M., Unnikrishnan, V. K., George, Sajan D., Kartha, V. B., Chidangil, Santhosh
Format: Article
Language:English
Subjects:
Biochemistry
Biological and Medical Physics
Biological Techniques
Biomarkers
Biomedical and Life Sciences
Biomedical materials
Biophysics
Body fluids
Cell Biology
COVID-19
Fourier analysis
Fourier transforms
Life Sciences
Membrane Biology
Nanotechnology
Optics
Personal health
Photonics
Review
Saliva
Surface plasmon resonance
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Summary:Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.
ISSN:1867-2450
1867-2469
DOI:10.1007/s12551-021-00807-8