Recent Advancement in Anticancer Activity of Clinacanthus nutans (Burm. f.) Lindau

Clinacanthus nutans is a traditional medicinal herb that is applied for the therapy of snake bites, skin infection, herpes infection, burns, scalds, dysentery, and diabetes. Clinacanthus nutans is also used to treat several cancers, including breast, cervical, colon, gastric, head and neck, liver, l...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2021, Vol.2021, p.1-13
Main Authors: Lin, Chung-Ming, Chen, Hsin-Han, Lung, Chi-Wen, Chen, Hui-Jye
Format: Article
Language:English
Subjects:
Alternative medicine
Antioxidants
Antitumor activity
Apoptosis
Breast
Breast cancer
Cell cycle
Clinacanthus nutans
Colon
Cytotoxicity
Diabetes mellitus
Dysentery
Flavonoids
Fractionation
Head and neck
Herbal medicine
Lymphoma
Medicinal plants
Molecular modelling
Pancreas
Review
Skin cancer
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Summary:Clinacanthus nutans is a traditional medicinal herb that is applied for the therapy of snake bites, skin infection, herpes infection, burns, scalds, dysentery, and diabetes. Clinacanthus nutans is also used to treat several cancers, including breast, cervical, colon, gastric, head and neck, liver, lung, pancreatic, and skin cancers, as well as lymphoma and leukemia; however, the underlying mechanisms of its anticancer activity remained undetermined. We searched PubMed and Google with key words “Clinacanthus nutans and cancer” and collected recent papers of Clinacanthus nutans with anticancer activity. We focused on the preparation, effects, and action mechanisms of Clinacanthus nutans extracts on various types of cancers. We hope that this mini review can help update our knowledge about active components, effects, and molecular mechanisms of extracts from this promising herb Clinacanthus nutans for ongoing studies and speed up its clinical application in the future.
ISSN:1741-427X
1741-4288
DOI:10.1155/2021/5560502