Modulatory effect of cashew (Anacardiumoccidentale L.) nut supplemented diet on fertility activity of clomiphene citrate in male rats

Increasing concern has been expressed about the declining sperm count of humans and the potential fertility effects of clomiphene citrate, a synthetic oestrogen-antagonist on human reproductive health in the last few decades. This study aims to investigate the influence of cashew nut supplemented di...

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Bibliographic Details
Published in:Biomedical journal 2021-04, Vol.44 (2), p.190-200
Main Authors: Akomolafe, Seun Funmilola, Aina, Babatunde, Bajulaye, Jumoke, Ogundare, Iyadunni, Olulade, Damola, Adeniji, Rebecca, Fatuase, Faith, Olojo-Kosoko, Ayomide, Ganiyu, Oboh, Asogwa, Nnaemeka Tobechukwu
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Language:English
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Summary:Increasing concern has been expressed about the declining sperm count of humans and the potential fertility effects of clomiphene citrate, a synthetic oestrogen-antagonist on human reproductive health in the last few decades. This study aims to investigate the influence of cashew nut supplemented diet on fertility activity of clomiphene citrate in male rats. The rats were divided into six groups n = 6: rats fed basal diet; rats fed basal diet and then given clomiphene citrate (cc) orally; rats fed diet supplemented with 10% processed cashew nut and given cc orally; and rat fed diet supplemented with 20% processed cashew nut and given cc orally; rats fed diet supplemented with 10% processed cashew nut and rat fed diet supplemented with 20% processed cashew nut for fourteen days. The results revealed that there was a significant (p 
ISSN:2319-4170
2320-2890
DOI:10.1016/j.bj.2019.12.005