Acyl metalloids: conformity and deviation from carbonyl reactivity

Once considered as mere curiosities, acyl metalloids are now recognized for their utility in enabling chemical synthesis. This perspective considers the reactivity displayed by acylboron, -silicon, -germanium, and tellurium species. By highlighting the role of these species in various transformation...

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Bibliographic Details
Published in:Chemical science (Cambridge) 2021-04, Vol.12 (15), p.5346-536
Main Authors: Holownia, Aleksandra, Apte, Chirag N, Yudin, Andrei K
Format: Article
Language:English
Subjects:
Carbonyls
Chemical synthesis
Chemistry
Germanium
Metalloids
Tellurium
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Summary:Once considered as mere curiosities, acyl metalloids are now recognized for their utility in enabling chemical synthesis. This perspective considers the reactivity displayed by acylboron, -silicon, -germanium, and tellurium species. By highlighting the role of these species in various transformations, we demonstrate how differences between the comprising elements result in varied reaction outcomes. While acylboron compounds are primarily used in polar transformations, germanium and tellurium species have found utility as radical precursors. Applications of acylsilanes are comparatively more diverse, owing to the possibility to access both radical and polar chemistry. Originally considered as fundamental curiosities, acyl metalloids have proven to be useful tools in synthesis. This perspective aims to highlight the modes of reactivity accessible to boron, silicon, germanium and tellurium species.
ISSN:2041-6520
2041-6539
DOI:10.1039/d1sc00077b