Detection of vaccine-derived poliovirus circulation by environmental surveillance in the absence of clinical cases

On August 25, 2019, the Noguchi Memorial Institute for Medical Research notified the confirmation of a circulating-vaccine-derived poliovirus type-2 (cVDPV2) from the Agbogbloshie environmental surveillance (AES) site, in the Greater Accra Region. A field investigation of the outbreak was conducted...

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Bibliographic Details
Published in:Human vaccines & immunotherapeutics 2021-07, Vol.17 (7), p.2117-2124
Main Authors: Odoom, John Kofi, Obodai, Evangeline, Boateng, Gifty, Diamenu, Stanley, Attiku, Keren, Avevor, Patrick, Duker, Ewurabena, Boahene, Bismarck, Eshun, Miriam, Gberbie, Emmanuel, Opare, Joseph Kwadwo Larbi
Format: Article
Language:English
Subjects:
Agbobloshie - Accra
Child
circulating vaccine-derived poliovirus
Environmental Monitoring
Ghana
Humans
mOPV
Nigeria
Polio
Poliomyelitis - epidemiology
Poliomyelitis - prevention & control
Poliovirus
Poliovirus Vaccine, Oral
Research Paper
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Summary:On August 25, 2019, the Noguchi Memorial Institute for Medical Research notified the confirmation of a circulating-vaccine-derived poliovirus type-2 (cVDPV2) from the Agbogbloshie environmental surveillance (AES) site, in the Greater Accra Region. A field investigation of the outbreak was conducted to describe the results of epidemiological and laboratory investigations, and control efforts. We conducted a descriptive investigation, records review, and active-case-search. Caregivers were interviewed on the vaccination status of their children; knowledge, attitude, and practices on polio prevention; water, sanitation and hygiene practices, and health-seeking behaviors. Stool from healthy children
ISSN:2164-5515
2164-554X
DOI:10.1080/21645515.2020.1852009