Chronic Kidney Disease and Atherosclerosis: An Important Implication of Carotid Intima-Media Thickness

Recently, noninvasive simple methods including carotid intima-media thickness (IMT), pulse wave velocity (PWV), ankle-brachial index (ABI), flow-mediated vasodilatation (FMD), and coronary artery calcification score (CACS) are available to evaluate atherosclerotic vascular damage. These parameters c...

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Bibliographic Details
Published in:Journal of Atherosclerosis and Thrombosis 2021/05/01, Vol.28(5), pp.471-473
Main Authors: Ohtake, Takayasu, Kobayashi, Shuzo
Format: Article
Language:English
Subjects:
Atherosclerosis
Carotid intima-media thickness
Chronic kidney disease
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Summary:Recently, noninvasive simple methods including carotid intima-media thickness (IMT), pulse wave velocity (PWV), ankle-brachial index (ABI), flow-mediated vasodilatation (FMD), and coronary artery calcification score (CACS) are available to evaluate atherosclerotic vascular damage. These parameters could provide reproducible and reliable information and are used not only as risk assessment and predicting factors for future cardiovascular (CV) events but also as tools to evaluate the efficacy of interventional treatment. A vicious association might exist between chronic kidney disease (CKD) and atherosclerosis. Carotid max-IMT is increased in patients with CKD even in its early stage, and has an impact as a predictor of future CV events and deaths in predialysis and dialysis CKD patients. Decreased renal function was associated with accelerated increase of carotid IMT.
ISSN:1340-3478
1880-3873
DOI:10.5551/jat.ED146