Acute kidney injury precipitating myocardial injury in a young male with COVID‐19

A systemic inflammatory response could contribute to hypoperfusion-related injury of the renal tubules,4 with evidence suggesting that a direct cytopathic effect of SARS-CoV-2 on the kidneys is also possible. The angiotensin-converting-enzyme 2 receptors, essential for viral uptake by host cells, ar...

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Bibliographic Details
Published in:Internal Medicine Journal 2021-05, Vol.51 (5), p.816-817
Main Authors: Daniels, Natasha F., Ridwan, Raiiq
Format: Article
Language:English
Subjects:
COVID-19
Letter to the Editor
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Summary:A systemic inflammatory response could contribute to hypoperfusion-related injury of the renal tubules,4 with evidence suggesting that a direct cytopathic effect of SARS-CoV-2 on the kidneys is also possible. The angiotensin-converting-enzyme 2 receptors, essential for viral uptake by host cells, are highly expressed on podocytes and tubule epithelial cells.5 The subsequent myopericarditis secondary to COVID-19 is a phenomenon characterised in other reports.6 His ECG changes showed new lateral and inferior T wave inversion suggestive of an acute cardiac injury. [...]this patient presented with an AKI prior to developing any respiratory symptoms, suggesting that infection with SARS-CoV2 could result in significant end-organ damage prior to respiratory involvement. 1.
ISSN:1444-0903
1445-5994
DOI:10.1111/imj.14977