Brain death and management of the potential donor

One of the first attempts to define brain death (BD) dates from 1963, and since then, the diagnosis criteria of that entity have evolved. In spite of the publication of practice parameters and evidence-based guidelines, BD is still causing concern and controversies in the society. The difficulties i...

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Bibliographic Details
Published in:Neurological sciences 2021-09, Vol.42 (9), p.3541-3552
Main Authors: Yoshikawa, Marcia Harumy, Rabelo, Nícollas Nunes, Welling, Leonardo Christiaan, Telles, João Paulo Mota, Figueiredo, Eberval Gadelha
Format: Article
Language:English
Subjects:
Brain death
Death
Diagnosis
Medicine
Medicine & Public Health
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Psychiatry
Review
Review Article
Transplantation
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Summary:One of the first attempts to define brain death (BD) dates from 1963, and since then, the diagnosis criteria of that entity have evolved. In spite of the publication of practice parameters and evidence-based guidelines, BD is still causing concern and controversies in the society. The difficulties in determining brain death and making it understood by family members not only endorse futile therapies and increase health care costs, but also hinder the organ transplantation process. This review aims to give an overview about the definition of BD, causes, physiopathology, diagnosis criteria, and management of the potential brain-dead donor. It is important to note that the BD determination criteria detailed here follow the AAN’s recommendations, but the standard practice for BD diagnosis varies from one country to another.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-021-05360-6