Takotsubo Syndrome—Is There a Need for CMR?

Purpose of Review Takotsubo syndrome (TTS) is a transient but severe myocardial dysfunction that has been known for decades and is still to be fully understood regarding its clinical presentations and pathophysiological mechanisms. Cardiac magnetic resonance (CMR) imaging plays a key role in the com...

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Bibliographic Details
Published in:Current heart failure reports 2021-08, Vol.18 (4), p.200-210
Main Authors: Jensch, Philipp-Johannes, Stiermaier, Thomas, Eitel, Ingo
Format: Article
Language:English
Subjects:
Cardiac Surgery
Cardiology
Heart
Heart Failure
Heart Ventricles
Humans
Imaging
Internal Medicine
Invited
Invited Commentary
Medicine
Medicine & Public Health
Radiology
Takotsubo Cardiomyopathy - diagnostic imaging
Vascular Surgery
Ventricular Function, Left
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Summary:Purpose of Review Takotsubo syndrome (TTS) is a transient but severe myocardial dysfunction that has been known for decades and is still to be fully understood regarding its clinical presentations and pathophysiological mechanisms. Cardiac magnetic resonance (CMR) imaging plays a key role in the comprehensive analysis of patients with TTS in acute and follow-up examinations. In this review, we focus on the major advantages and latest evolutions of CMR in diagnosis and prognostication of TTS and discuss future perspectives and needs in the field of research and cardiovascular imaging in TTS. Recent Findings Specific CMR criteria for TTS diagnosis at the time of acute presentation are established. In addition to identifying the typical regional wall motion abnormalities, CMR allows for precise quantification of right ventricular and left ventricular (LV) function, the assessment of additional abnormalities/complications (e.g. pericardial and/or pleural effusion, LV thrombi), and most importantly myocardial tissue characterization (myocardial oedema, inflammation, necrosis/fibrosis). Summary CMR enables a comprehensive assessment of the entire spectrum of functional and structural changes that occur in patients with TTS and may have also a prognostic impact. CMR can distinguish between TTS and other important differential diagnoses (myocarditis, myocardial infarction) with direct consequences on medical therapy.
ISSN:1546-9530
1546-9549
1546-9549
DOI:10.1007/s11897-021-00518-x