Rates of Bile Acid Diarrhoea After Cholecystectomy: A Multicentre Audit

Introduction Bile acid diarrhoea (BAD) can occur due to disruption to the enterohepatic circulation, e.g. following cholecystectomy. Post-cholecystectomy diarrhoea has been reported in 2.1–57.2% of patients; however, this is not necessarily due to BAD. The aim of this study was to determine the rate...

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Bibliographic Details
Published in:World journal of surgery 2021-08, Vol.45 (8), p.2447-2453
Main Authors: Farrugia, Alexia, Attard, Joseph Anthony, Hanmer, Stuart, Bullock, Stuart, McKay, Siobhan, Al-Azzawi, Marwa, Ali, Roshneen, Bond-Smith, Giles, Colleypriest, Ben, Dyer, Sarah, Masterman, Benjamin, Okocha, Michael, Osborne, Alan, Patel, Rikhilroy, Sallam, Mahmoud, Selveraj, Emmanuel, Shalaby, Samar, Sun, Wenrui, Todd, Fraser, Ward, Joel, Windle, Rebecca, Khan, Saboor, Williams, Nigel, Arasaradnam, Ramesh P.
Format: Article
Language:English
Subjects:
Abdominal Surgery
Acids
Bile
Bile Acids and Salts
Cardiac Surgery
Cholecystectomy
Cholecystectomy - adverse effects
Computed tomography
Demography
Diagnosis
Diarrhea
Diarrhea - epidemiology
Diarrhea - etiology
Endoscopy
General Surgery
Humans
Investigations
Laparoscopy
Medicine
Medicine & Public Health
Original Scientific Report
Patients
Prevalence
Retention time
Retrospective Studies
Surgery
Thoracic Surgery
Time lag
Vascular Surgery
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Summary:Introduction Bile acid diarrhoea (BAD) can occur due to disruption to the enterohepatic circulation, e.g. following cholecystectomy. Post-cholecystectomy diarrhoea has been reported in 2.1–57.2% of patients; however, this is not necessarily due to BAD. The aim of this study was to determine the rates of bile acid diarrhoea diagnosis after cholecystectomy and to consider investigation practices. Methods A retrospective analysis of electronic databases from five large centres detailing patients who underwent laparoscopic cholecystectomy between 2013 and 2017 was cross-referenced with a list of patients who underwent 75 SeHCAT testing. A 7-day retention time of
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-021-06147-8