Direct hemoperfusion using a polymyxin B‐immobilized polystyrene column for COVID‐19

Objective To evaluate the efficacy and safety of direct hemoperfusion using a polymyxin B‐immobilized polystyrene column (PMX‐DHP) in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐positive pneumonia patients. Methods This study was a case series conducted at a designated infectious di...

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Bibliographic Details
Published in:Journal of clinical apheresis 2021-06, Vol.36 (3), p.313-321
Main Authors: Katagiri, Daisuke, Ishikane, Masahiro, Asai, Yusuke, Izumi, Shinyu, Takasaki, Jin, Katsuoka, Hiyori, Kondo, Isao, Ide, Satoshi, Nakamura, Keiji, Nakamoto, Takato, Nomoto, Hidetoshi, Akiyama, Yutaro, Miyazato, Yusuke, Suzuki, Tetsuya, Kinoshita, Noriko, Ogawa, Tatsunori, Togano, Tomiteru, Suzuki, Manabu, Hashimoto, Masao, Sakamoto, Keita, Kusaba, Yusaku, Katsuno, Takashi, Fukaya, Takashi, Hojo, Masayuki, Sugiyama, Masaya, Mizokami, Masashi, Okamoto, Tatsuya, Kimura, Akio, Noiri, Eisei, Ohmagari, Norio, Hinoshita, Fumihiko, Sugiyama, Haruhito
Format: Article
Language:English
Subjects:
COVID-19
cytokine
Cytokines
pneumonia
Severe acute respiratory syndrome coronavirus 2
Steroids
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Summary:Objective To evaluate the efficacy and safety of direct hemoperfusion using a polymyxin B‐immobilized polystyrene column (PMX‐DHP) in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐positive pneumonia patients. Methods This study was a case series conducted at a designated infectious diseases hospital. Twelve SARS‐CoV‐2‐positive patients with partial pressure of arterial oxygen/percentage of inspired oxygen (P/F) ratio 
ISSN:0733-2459
1098-1101
DOI:10.1002/jca.21861