Successful single kidney transplantation from pediatric donors less than or equal to 10 kg to adult recipient: a retrospective cohort study

• Published in: Translational pediatrics 2021-06, Vol.10 (6), p.1618-1629
• Main Authors: Chen, Chuxiao, Su, Xiaojun, Wu, Chenglin, Liu, Longshan, Zhang, Huanxi, Deng, Ronghai, Fu, Qian, Yuan, Xiaopeng, Zheng, Yitao, Qiu, Jiang, Chen, Guodong, Huang, Gang, Deng, Suxiong, Fei, Jiguang, Chen, Lizhong, Li, Jun, Wang, Changxi
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 2224-4336; 2224-4344; 2224-4344
• DOI: 10.21037/tp-21-23

BACKGROUNDKidneys from very small pediatric donors (≤10 kg) are underutilized. Compared to en bloc kidney transplantation (EBKT), single kidney transplantation (SKT) can maximize donor resources. However, it remains unknown whether it's appropriate to perform SKTs from donors weighing ≤10 kg. METHODSA total of 35 adult recipients undergoing kidney transplantation from donors weighing ≤10 kg at our center from December 2014 to December 2019 were included and grouped into SKT group (n=20) and EBKT group (n=15). Transplant outcomes were retrospectively analyzed and compared between 2 groups. RESULTSThe 1-year and 3-year death-censored graft survival in SKT group was 95%, it is not significantly higher than that in EBKT group (80%, log-rank test, P=0.38). Significant improvement in estimated glomerular filtration rate (eGFR) was noted in both groups, despite eGFR at 1 year was lower in the SKT group (P