Clinical profile and contemporary management of patients with heart failure with preserved ejection fraction: results from the CHECK-HF registry

• Published in: Netherlands heart journal 2021-07, Vol.29 (7-8), p.370-376
• Main Authors: Uijl, A., Veenis, J. F., Brunner-La Rocca, H. P., van Empel, V., Linssen, G. C. M., Asselbergs, F. W., van der Lee, C., Eurlings, L. W. M., Kragten, H., Al-Windy, N. Y. Y., van der Spank, A., Koudstaal, S., Brugts, J. J., Hoes, A. W.
• Format: Article
• Language: English
• Subjects: Age; Beta blockers; Blood pressure; Body mass index; Cardiac arrhythmia; Cardiology; Cardiovascular disease; Chronic obstructive pulmonary disease; Comorbidity; Coronary vessels; Diabetes; Ejection fraction; Endocrine system; Heart failure; Hypertension; Medical Education; Medicine; Medicine & Public Health; Original; Original Article; Patients; Regression analysis; Thyroid gland; Vein & artery diseases; Women
• ISSN: 1568-5888; 1876-6250
• DOI: 10.1007/s12471-020-01534-7

Background Clinical management of heart failure with preserved ejection fraction (HFpEF) centres on treating comorbidities and is likely to vary between countries. Thus, to provide insight into the current management of HFpEF, studies from multiple countries are required. We evaluated the clinical profiles and current management of patients with HFpEF in the Netherlands. Methods We included 2153 patients with HFpEF (defined as a left ventricular ejection fraction ≥ 50%) from the CHECK-HF registry, which included patients from 2013 to 2016. Results Median age was 77 (IQR 15) years, 55% were women and the most frequent comorbidities were hypertension (51%), renal insufficiency (45%) and atrial fibrillation (AF, 38%). Patients between 65 and 80 years and those over 80 years had on average more comorbidities (up to 64% and 74%, respectively, with two or more comorbidities) than patients younger than 65 years (38% with two or more comorbidities, p -value