Guided Tissue Regeneration Treatment Yields Better Results in Class II Furcations in the Mandible Than in the Maxilla: A Retrospective Study

• Published in: International journal of environmental research and public health 2021-07, Vol.18 (14), p.7447
• Main Authors: Dorj, Odontuya, Lee, Wei-Fang, Salamanca, Eisner, Pan, Yu-Hwa, Wu, Yi-Fan, Hsu, Yung-Szu, Lin, Jerry C. Y., Lin, Yu-De, Choy, Cheuk-Sing, Chang, Wei-Jen
• Format: Article
• Language: English
• Subjects: Bone grafts; Clinical outcomes; Collagen; Debridement; Defects; Grafting; Grafts; Maxilla; Membranes; Molars; Oral hygiene; Regeneration; Substitute bone; Systematic review; Teeth; Tissue engineering; Xenografts; Xenotransplantation
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph18147447

Absorbable porcine collagen membrane with a bovine bone graft can be considered for regenerative treatment in periodontal class II furcation defects. We evaluated the clinical efficacy of guided tissue regeneration (GTR) treatment with bovine bone xenograft and a porcine collagen membrane in molars with class II furcations. Probing depth (PD), clinical attachment level (CAL), and bone level (BL) were recorded at baseline and at 3, 6, and 9 months postoperatively. Thirty class II furcation defects from the lower and upper molars were assessed. Significant improvements in PD and CAL were observed from baseline to 9 months in all groups (p < 0.01). BL improved in all groups except group A in the upper molars in radiographic assessment (p < 0.05). The lower and upper molars showed PD reduction of 50.5% ± 7.44% and 46.2% ± 11.2%, respectively, at 9 months (p = 0.044). In furcations of 1–3 mm, the lower and upper molars showed PD reductions of 51.2% ± 4.49% and 36.5% ± 16.14%, respectively (p = 0.035). The lower and upper molars showed a CAL gain of 51.1% ± 4.64% and 33.6% ± 18.8%, respectively (p = 0.037). Thus, GTR with bovine bone graft and porcine collagen membrane yielded good results in class II furcations, with better results in the lower than in the upper molars.