Preeclampsia and Cardiovascular Risk for Offspring

There is growing evidence of long-term cardiovascular sequelae in children after in utero exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during pregnancy increase the risk of hypertension, stroke, diabetes, and cardiovascular disease (CVD) in the offspring later in life....

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Bibliographic Details
Published in:Journal of clinical medicine 2021-07, Vol.10 (14), p.3154
Main Authors: Wojczakowski, Wiktor, Kimber-Trojnar, Żaneta, Dziwisz, Filip, Słodzińska, Magdalena, Słodziński, Hubert, Leszczyńska-Gorzelak, Bożena
Format: Article
Language:English
Subjects:
Body mass index
Clinical medicine
Congenital diseases
Mortality
Preeclampsia
Premature birth
Review
Womens health
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Summary:There is growing evidence of long-term cardiovascular sequelae in children after in utero exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during pregnancy increase the risk of hypertension, stroke, diabetes, and cardiovascular disease (CVD) in the offspring later in life. The mechanisms associated with CVD seem to be a combination of genetic, molecular, and environmental factors which can be defined as fetal and postnatal programming. The aim of this paper is to discuss the relationship between pregnancy complicated by preeclampsia and possibility of CVD in the offspring. Unfortunately, due to its multifactorial nature, a clear dependency mechanism between preeclampsia and CVD is difficult to establish.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm10143154