Comparison of Efficacy among Three Radiofrequency Ablation Techniques for Treating Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Radiofrequency ablation (RFA) was first introduced for treating knee osteoarthritis (OA) in 2010 and has emerged as a minimally invasive treatment option. Three RFA techniques have been adopted for treating knee OA, including conventional, pulsed, and cooled RFA. However, the efficacy among differen...

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Bibliographic Details
Published in:International journal of environmental research and public health 2021-07, Vol.18 (14), p.7424
Main Authors: Chou, Shih-Hsiang, Shen, Po-Chih, Lu, Cheng-Chang, Liu, Zi-Miao, Tien, Yin-Chun, Huang, Peng-Ju, Chou, Cheng-Ming, Shih, Chia-Lung
Format: Article
Language:English
Subjects:
Ablation
Arthritis
Biomedical materials
Electric stimulation therapy
Knee
Meta-analysis
Osteoarthritis
Pain
Patients
Radio frequency
Regression analysis
Software
Text analysis
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Summary:Radiofrequency ablation (RFA) was first introduced for treating knee osteoarthritis (OA) in 2010 and has emerged as a minimally invasive treatment option. Three RFA techniques have been adopted for treating knee OA, including conventional, pulsed, and cooled RFA. However, the efficacy among different RFA techniques in the treatment of knee OA is still unclear. Three electronic databases were systematically searched for relevant articles, including PubMed, Embase, and Cochrane Library. A meta-analysis of articles that investigated the use of RFA techniques in the treatment of knee OA was conducted to pool the effect size in pain before and after treatment. A total of 20 eligible articles (including 605 patients) were included for our meta-analysis. After treatment, the patients had significant improvements in pain for all three RFA techniques when compared with the baseline level for the 1, 3-, and 6-month follow-ups (p < 0.00001). However, there were no significant differences in the efficacy among the three RFA techniques for all follow-up visits (p > 0.05). The three RFA techniques demonstrated a significant improvement in pain for up to 6 months after treatment. Comparing the efficacy of the three RFA techniques in the treatment of knee OA, our results showed that no significant differences in pain relief among the three RFA techniques were observed at the 1-, 3-, 6, and 12-month follow-up visits.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph18147424