Cutaneous Events Associated with Immunotherapy of Melanoma: A Review

Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, th...

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Bibliographic Details
Published in:Journal of clinical medicine 2021-07, Vol.10 (14), p.3047
Main Authors: Burzi, Lorenza, Alessandrini, Aurora Maria, Quaglino, Pietro, Piraccini, Bianca Maria, Dika, Emi, Ribero, Simone
Format: Article
Language:English
Subjects:
Antigens
Apoptosis
Clinical medicine
Cytokines
Cytotoxicity
Immune system
Immunotherapy
Lymphocytes
Medical prognosis
Melanoma
Metastasis
Patients
Review
Skin
Vitiligo
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Summary:Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, the Sutton phenomenon, melanosis and hair and nail toxicities.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm10143047