Do Bioactive Food Compound with Avena sativa L., Linum usitatissimum L. and Glycine max L. Supplementation with Moringa oleifera Lam. Have a Role against Nutritional Disorders? An Overview of the In Vitro and In Vivo Evidence

• Published in: Nutrients 2021-07, Vol.13 (7), p.2294
• Main Authors: Ferreira, Rosângela Dos Santos, Mendonça, Lígia Aurélio Bezerra Maranhão, Santos, Cristiane Dos, Hiane, Priscila Aiko, Matias, Rosemary, Franco, Octávio Luiz, de Oliveira, Ademir Kleber Morbeck, do Nascimento, Valter Aragão, Pott, Arnildo, Carvalho, Cristiano Marcelo Espinola, Guimarães, Rita de Cássia Avellaneda
• Format: Article
• Language: English
• Subjects: Animals; Antioxidants; Avena; Avena sativa; Bioactive compounds; Biological activity; Biomedical materials; Broths; Carcinogenesis; Carcinogens; Cardiovascular disease; Cardiovascular diseases; Cholesterol; Chronic illnesses; Clinical nutrition; Cookies; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Dietary fiber; Dietary Supplements; Dyslipidemia; Fatty acids; Flax; Food; Fruits; Functional Food; Functional foods & nutraceuticals; Glucose; Glycine max; Health services; Herbal medicine; Humans; In vivo methods and tests; Inflammatory diseases; Insulin; Linum usitatissimum; Malnutrition; Medicinal plants; Metabolic disorders; Metabolic syndrome; Metabolites; Moringa oleifera; Nutrition; Nutrition Disorders - therapy; Nutrition therapy; Nutrition Therapy - methods; Oats; Obesity; Phytochemicals - therapeutic use; Prevention; Purees; Review; Salads; Seeds; Soups; Synergistic effect; Triglycerides; Vegetables; Viscosity; Vitamins
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu13072294

Functional clinical nutrition is an integrative science; it uses dietary strategies, functional foods and medicinal plants, as well as combinations thereof. Both functional foods and medicinal plants, whether associated or not, form nutraceuticals, which can bring benefits to health, in addition to being included in the prevention and treatment of diseases. Some functional food effects from L. (oats), L. (brown flaxseed), L. (soya) and have been proposed for nutritional disorders through in vitro and in vivo tests. A formulation called a bioactive food compound (BFC) showed efficiency in the association of oats, flaxseed and soy for dyslipidemia and obesity. In this review, we discuss the effects of BFC in other nutritional disorders, as well as the beneficial effects of in obesity, cardiovascular disease, diabetes mellitus type 2, metabolic syndrome, intestinal inflammatory diseases/colorectal carcinogenesis and malnutrition. In addition, we hypothesized that a BFC enriched with could present a synergistic effect and play a potential benefit in nutritional disorders. The traditional consumption of preparations can allow associations with other formulations, such as BFC. These nutraceutical formulations can be easily accepted and can be used in sweet preparations (fruit and/or vegetable juices, fruit and/or vegetable vitamins, porridges, yogurt, cream, mousses or fruit salads, cakes and cookies) or savory (vegetable purees, soups, broths and various sauces), cooked or not. These formulations can be low-cost and easy-to-use. The association of bioactive food substances in dietary formulations can facilitate adherence to consumption and, thus, contribute to the planning of future nutritional interventions for the prevention and adjuvant treatment of the clinical conditions presented in this study. This can be extended to the general population. However, an investigation through clinical studies is needed to prove applicability in humans.