Serum estradiol level on the day of trigger as a predictor of number of metaphase II oocytes from IVF antagonist cycles and subsequent impact on pregnancy rates

This study aimed to examine the association between serum estradiol levels and number of metaphase II oocytes harvested after in vitro fertilization cycles used in embryo transfers and the subsequent impact on pregnancy rates. This observational analytical retrospective study was carried out in 2010...

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Bibliographic Details
Published in:JBRA assisted reproduction 2021, Vol.25 (3), p.447-452
Main Authors: Morales, Héctor Salvador Godoy, Guiot, Miguel Loyo, López, Germán Gabriel Palacios, Córtes, Daniel Vieyra, Maldonado, Berenice Flores, Hernández, Hilda Sánchez, Torres, Griselda Claribel Reyes, Camacho, Francisco Miguel Rojas, Montoya, Gabriela Ayala
Format: Article
Language:English
Subjects:
Age groups
Data collection
Estradiol
Female
Fertility
Fertilization in Vitro
Humans
In vitro fertilization
Infertility
Medical records
Metaphase
Normal distribution
Oocytes
Original
Ovaries
Ovulation Induction
Patients
Pregnancy
Pregnancy Rate
Regression analysis
Reproducibility of Results
Retrospective Studies
Variables
Citations: Items that cite this one
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Summary:This study aimed to examine the association between serum estradiol levels and number of metaphase II oocytes harvested after in vitro fertilization cycles used in embryo transfers and the subsequent impact on pregnancy rates. This observational analytical retrospective study was carried out in 2010-2018 at the Angeles del Pedregal Hospital. It included 181 cases and looked into the number of metaphase II oocytes to predict pregnancy rates. Statistical analysis was based on the calculation of correlations between variables and logistic regressions. Estradiol levels increased with the number of oocytes by a median correlation (r=0.482, p=0.000). On the day of trigger, estradiol levels predicted the number of retrieved oocytes with 23% reliability (R2=0.232, p=0.000); a linear trend correlation of r=0.489, p=0.000 was found between estradiol levels on the day of trigger and number of metaphase II oocytes. Serum estradiol on the day of trigger as a predictor of metaphase II oocytes in antagonist cycles encourages greater oocyte maturity and fertilization, whereas, in isolation, it does not determine the pregnancy achievement.
ISSN:1518-0557
1517-5693
1518-0557
DOI:10.5935/1518-0557.20210007