mRNA Transport and Local Translation in Glia

Though mRNA transport and local translation are extensively studied in neurons, emerging evidence supports that these cellular processes are also abundant in non-neuronal glial cells. Here, we explore mechanisms of mRNA transport and local translation in oligodendrocytes, astrocytes, microglia, radi...

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Bibliographic Details
Published in:Trends in cell biology 2021-06, Vol.31 (6), p.419-423
Main Authors: Meservey, Lindsey Madsen, Topkar, Ved V., Fu, Meng-meng
Format: Article
Language:English
Subjects:
mRNA
RNA transport
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Summary:Though mRNA transport and local translation are extensively studied in neurons, emerging evidence supports that these cellular processes are also abundant in non-neuronal glial cells. Here, we explore mechanisms of mRNA transport and local translation in oligodendrocytes, astrocytes, microglia, radial glia, and their functions in development, structure, and intercellular interactions.
ISSN:0962-8924
1879-3088
DOI:10.1016/j.tcb.2021.03.006