Early CT findings after interstitial radiation therapy for primary malignant brain tumors

The CT findings after interstitial radiation therapy for brain tumors have not been extensively described. We evaluated retrospectively the CT scans of 13 patients who were treated with brachytherapy for malignant glioma. We found no typical CT appearance that differentiates recurrent tumor from rad...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 1988-11, Vol.9 (6), p.1177-1180
Main Authors: Tolly, TL, Bruckman, JE, Czarnecki, DJ, Frazin, LJ, Lewis, HJ, Richards, MJ, Adamkiewicz, JJ, Jr
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Brachytherapy - adverse effects
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - radiotherapy
Female
Glioblastoma - diagnostic imaging
Glioblastoma - radiotherapy
Humans
Investigative techniques, diagnostic techniques (general aspects)
Iridium Radioisotopes - administration & dosage
Iridium Radioisotopes - therapeutic use
Male
Medical sciences
Middle Aged
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - radiotherapy
Nervous system
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Retrospective Studies
Time Factors
Tomography, X-Ray Computed
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Summary:The CT findings after interstitial radiation therapy for brain tumors have not been extensively described. We evaluated retrospectively the CT scans of 13 patients who were treated with brachytherapy for malignant glioma. We found no typical CT appearance that differentiates recurrent tumor from radiation effect. After undergoing brachytherapy, eight of the 13 patients scanned demonstrated enhancement of brain tissue beyond the margins of the original enhancing tumor mass. In most cases, the pattern of enhancement diminished and extended more peripherally from the central necrotic area with time. We also report a new CT finding of focal calcification developing at the site of the radioactive implant.
ISSN:0195-6108
1936-959X