MR imaging in acute multiple sclerosis: ringlike appearance in plaques suggesting the presence of paramagnetic free radicals

MR studies in three patients with multiple sclerosis have shown clearly defined rings within plaques of demyelination, having signal characteristics consistent with the presence of paramagnetic material. It is suggested that these appearances represent the presence of free radicals in the macrophage...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 1992-11, Vol.13 (6), p.1544-1546
Main Authors: Powell, T, Sussman, JG, Davies-Jones, GA
Format: Article
Language:English
Subjects:
Acute Disease
Brain - pathology
Case Reports
Free Radicals
Humans
Magnetic Resonance Imaging
Multiple Sclerosis - pathology
Online Access:Get full text
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Summary:MR studies in three patients with multiple sclerosis have shown clearly defined rings within plaques of demyelination, having signal characteristics consistent with the presence of paramagnetic material. It is suggested that these appearances represent the presence of free radicals in the macrophage layer forming the margin of an acute plaque.
ISSN:0195-6108
1936-959X