Diffuse leptomeningeal gliomatosis with osteoblastic metastases and no evidence of intraaxial lesions

An autopsy-proved case of cerebral and medullary leptomeningeal gliomatosis and diffuse osteoblastic metastases without evidence of intraaxial tumor is described. MR findings included diffuse thickening of the cerebral and medullary leptomeninges on T1-weighted, proton density-weighted, and T2-weigh...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 1995-05, Vol.16 (5), p.1018-1020
Main Authors: Pingi, A, Trasimeni, G, Di Biasi, C, Gualdi, G, Piazza, G, Corsi, F, Chiappetta, F
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Bone Marrow - pathology
Brain Stem - pathology
Case Reports
Cerebral Cortex - pathology
Glioma - diagnosis
Glioma - pathology
Glioma - secondary
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Medulla Oblongata - pathology
Meningeal Neoplasms - diagnosis
Meningeal Neoplasms - pathology
Meninges - pathology
Neurology
Skull - pathology
Skull Neoplasms - diagnosis
Skull Neoplasms - pathology
Skull Neoplasms - secondary
Tumors of the nervous system. Phacomatoses
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Summary:An autopsy-proved case of cerebral and medullary leptomeningeal gliomatosis and diffuse osteoblastic metastases without evidence of intraaxial tumor is described. MR findings included diffuse thickening of the cerebral and medullary leptomeninges on T1-weighted, proton density-weighted, and T2-weighted images and abnormal enhancement of the sulci and cisterns of the cerebrum, brain stem, cerebellum, and medulla on postcontrast T1-weighted images. MR also showed several areas of replacement of the normal bone marrow of the skull. No intraaxial lesion was seen.
ISSN:0195-6108
1936-959X