A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children’s Hospitals Neonatal Consortium Severe BPD Group

Objective To compare three bronchopulmonary dysplasia (BPD) definitions against hospital outcomes in a referral-based population. Study design Data from the Children’s Hospitals Neonatal Consortium were classified by 2018 NICHD, 2019 NRN, and Canadian Neonatal Network (CNN) BPD definitions. Multivar...

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Bibliographic Details
Published in:Journal of perinatology 2022-01, Vol.42 (1), p.58-64
Main Authors: Vyas-Read, Shilpa, Logan, J. Wells, Cuna, Alain C., Machry, Joana, Leeman, Kristin T., Rose, Rebecca S., Mikhael, Michel, Wymore, Erica, Ibrahim, John W., DiGeronimo, Robert J., Yallapragada, Sushmita, Haberman, Beth E., Padula, Michael A., Porta, Nicolas F., Murthy, Karna, Nelin, Leif D., Coghill, Carl H., Zaniletti, Isabella, Savani, Rashmin C., Truog, William, Engle, William A., Lagatta, Joanne M.
Format: Article
Language:English
Subjects:
692/308/409
692/699/1785
692/700/1720
Bronchopulmonary Dysplasia - complications
Canada
Child
Children
Consortia
Dysplasia
Gestational Age
Hospitals
Humans
Infant
Infant, Newborn
Infant, Premature
Infants
Lung diseases
Medicine
Medicine & Public Health
Neonates
Newborn babies
Ostomy
Pediatric Surgery
Pediatrics
Population studies
Retrospective Studies
Tracheostomy
Tracheotomy
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Summary:Objective To compare three bronchopulmonary dysplasia (BPD) definitions against hospital outcomes in a referral-based population. Study design Data from the Children’s Hospitals Neonatal Consortium were classified by 2018 NICHD, 2019 NRN, and Canadian Neonatal Network (CNN) BPD definitions. Multivariable models evaluated the associations between BPD severity and death, tracheostomy, or length of stay, relative to No BPD references. Results Mortality was highest in 2019 NRN Grade 3 infants (aOR 225), followed by 2018 NICHD Grade 3 (aOR 145). Infants with lower BPD grades rarely died (
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01178-4