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Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children

Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV...

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Bibliographic Details
Published in:Journal of the Pediatric Infectious Diseases Society 2021-11, Vol.10 (10), p.967-969
Main Authors: Banerjee, Dithi, Sasidharan, Anjana, Abdulhamid, Ayah, Orosco, Esmeralda M, Watts, Jennifer L, Schuster, Jennifer E, Myers, Angela L, Weddle, Gina, Selvarangan, Rangaraj
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Language:English
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Summary:Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.
ISSN:2048-7207
2048-7193
2048-7207
DOI:10.1093/jpids/piab058