Digestive enzyme replacement relieves growth failure in preterm infants with poor exocrine pancreatic function: a retrospective case series

In orally fed preterm infants, poor weight gain may be linked to low fecal pancreatic elastase-1 (FPE-1) activity, indicative of exocrine pancreatic insufficiency. The objective of this study was the retrospective assessment of the effect of exogenous digestive enzyme replacement by gavage in preter...

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Bibliographic Details
Published in:European journal of pediatrics 2021-09, Vol.180 (9), p.2951-2958
Main Authors: Münch, Annette, Bührer, Christoph, Longardt, Ann Carolin
Format: Article
Language:English
Subjects:
Birth weight
Digestive enzymes
Elastase
Enzymes
Infants
Medicine
Medicine & Public Health
Neonates
Newborn babies
Original
Original Article
Pancreas
Pancreatic elastase
Pediatrics
Physical growth
Premature babies
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Summary:In orally fed preterm infants, poor weight gain may be linked to low fecal pancreatic elastase-1 (FPE-1) activity, indicative of exocrine pancreatic insufficiency. The objective of this study was the retrospective assessment of the effect of exogenous digestive enzyme replacement by gavage in preterm infants with growth failure and low FPE-1 (
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-021-04069-0