Clinical and Demographic Characteristics of Upper Limb Dystonia

ABSTRACT Background Knowledge of characteristics in upper limb dystonia remains limited, derived primarily from small, single‐site studies. Objective The objective of this study was to characterize demographic and clinical characteristics of upper limb dystonia from the Dystonia Coalition data set,...

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Bibliographic Details
Published in:Movement disorders 2020-11, Vol.35 (11), p.2086-2090
Main Authors: Norris, Scott A., Jinnah, Hyder A., Klein, Christine, Jankovic, Joseph, Berman, Brian D., Roze, Emmanuel, Mahajan, Abhimanyu, Espay, Alberto J., Murthy, Avinash V., Fung, Victor S.C., LeDoux, Mark S., Chang, Florence C.F., Vidailhet, Marie, Testa, Claudia, Barbano, Richard, Malaty, Irene A., Bäumer, Tobias, Loens, Sebastian, Wright, Laura J., Perlmutter, Joel S.
Format: Article
Language:English
Subjects:
alleviating maneuver
Demography
Dystonia
Dystonia - epidemiology
Dystonic Disorders - epidemiology
Female
Human health and pathology
Humans
Life Sciences
Male
Movement disorders
Muscle contraction
musician's cramp
Parkinson's disease
sensory trick
task‐specific
writer's cramp
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Summary:ABSTRACT Background Knowledge of characteristics in upper limb dystonia remains limited, derived primarily from small, single‐site studies. Objective The objective of this study was to characterize demographic and clinical characteristics of upper limb dystonia from the Dystonia Coalition data set, a large, international, multicenter resource. Methods We evaluated clinical and demographic characteristics of 367 participants with upper limb dystonia from onset, comparing across subcategories of focal (with and without dystonia spread) versus nonfocal onset. Results Focal onset occurred in 80%; 67% remained focal without spread. Task specificity was most frequent in this subgroup, most often writer's cramp and affecting the dominant limb (83%). Focal onset with spread was more frequent in young onset (
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.28223