Association of ocular blood flow and contrast sensitivity in normal tension glaucoma

Purpose To investigate the relationship of ocular blood flow (via arteriovenous passage time, AVP) and contrast sensitivity (CS) in healthy as well as normal tension glaucoma (NTG) subjects. Design Mono-center comparative prospective trial Methods Twenty-five NTG patients without medication and 25 h...

Full description

Saved in:
Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2021-08, Vol.259 (8), p.2251-2257
Main Authors: Kuerten, David, Fuest, Matthias, Walter, Peter, Mazinani, Babac, Plange, Niklas
Format: Article
Language:English
Subjects:
Acuity
Angiography
Basic Science
Blood flow
Correlation analysis
Fluorescein
Glaucoma
Image processing
Medicine
Medicine & Public Health
Ophthalmology
Retina
Visual field
Visual perception
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To investigate the relationship of ocular blood flow (via arteriovenous passage time, AVP) and contrast sensitivity (CS) in healthy as well as normal tension glaucoma (NTG) subjects. Design Mono-center comparative prospective trial Methods Twenty-five NTG patients without medication and 25 healthy test participants were recruited. AVP as a measure of retinal blood flow was recorded via fluorescein angiography after CS measurement using digital image analysis. Association of AVP and CS at 4 spatial frequencies (3, 6, 12, and 18 cycles per degree, cpd) was explored with correlation analysis. Results Significant differences regarding AVP, visual field defect, intraocular pressure, and CS measurement were recorded in-between the control group and NTG patients. In NTG patients, AVP was significantly correlated to CS at all investigated cpd (3 cpd: r =  − 0.432, p
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-021-05235-8