Multiple sclerosis in adolescents: CT and MR findings

The MR and CT findings in 12 adolescents with multiple sclerosis were compared with reported findings in adults. The adolescent group showed a more striking female predominance, more severe disease characteristics, and more frequent infratentorial involvement. Cortical atrophy and abnormal iron accu...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 1990-05, Vol.11 (3), p.489-494
Main Authors: Osborn, AG, Harnsberger, HR, Smoker, WR, Boyer, RS
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Brain - diagnostic imaging
Brain - pathology
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Multiple Sclerosis - diagnosis
Multiple Sclerosis - diagnostic imaging
Multiple Sclerosis - pathology
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Neurology
Sex Factors
Tomography, X-Ray Computed
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Summary:The MR and CT findings in 12 adolescents with multiple sclerosis were compared with reported findings in adults. The adolescent group showed a more striking female predominance, more severe disease characteristics, and more frequent infratentorial involvement. Cortical atrophy and abnormal iron accumulation in the basal ganglia were uncommon in the adolescents. Neither group demonstrated a correlation between symptom severity and either extent or location of disease as delineated by MR imaging. MR was more sensitive than CT in detecting demyelinating plaques.
ISSN:0195-6108
1936-959X