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CytoLyt® Fixation Significantly Inhibits MIB1 Immunoreactivity, whereas Alternative Ki67 Clone 30-9 is not Susceptible to the Inhibition: Critical Diagnostic Implications
CytoLyt® fixation substantially inhibits MIB1 immunoreactivity and may present a diagnostic pitfall in certain tumors, especially small cell carcinoma. The Ki67 30-9 clone shows adequate performance and we strongly recommend it for laboratories utilizing CytoLyt® collection media.
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Published in: | Cancer cytopathology 2019-08, Vol.127 (10), p.643-649 |
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container_end_page | 649 |
container_issue | 10 |
container_start_page | 643 |
container_title | Cancer cytopathology |
container_volume | 127 |
creator | Buonocore, Darren J. Konno, Fumiko Jungbluth, Achim A. Frosina, Denise Fayad, Mariam Edelweiss, Marcia Lin, Oscar Rekhtman, Natasha |
description | CytoLyt® fixation substantially inhibits MIB1 immunoreactivity and may present a diagnostic pitfall in certain tumors, especially small cell carcinoma. The Ki67 30-9 clone shows adequate performance and we strongly recommend it for laboratories utilizing CytoLyt® collection media. |
doi_str_mv | 10.1002/cncy.22170 |
format | article |
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source | Wiley-Blackwell Read & Publish Collection |
title | CytoLyt® Fixation Significantly Inhibits MIB1 Immunoreactivity, whereas Alternative Ki67 Clone 30-9 is not Susceptible to the Inhibition: Critical Diagnostic Implications |
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