Diabetic striatopathy

The patient had recent admission 4 weeks ago with increased drowsiness and raised capillary blood glucose reading of 935 mg/dL with elevated serum osmolality level at 321 mosmol/kg and no ketoacidosis (pH 7.404), resulting in the diagnosis of hyperosmolar hyperglycaemic syndrome (HHS). Chorea may im...

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Bibliographic Details
Published in:BMJ case reports 2021-08, Vol.14 (8), p.e244248
Main Authors: Iri, Takanobu, Yano, Hiroyuki, Kinjo, Mitsuyo
Format: Article
Language:English
Subjects:
Case reports
Diabetes
Diabetes Complications
Diabetes Mellitus
Dopamine
Dyskinesias
Glucose
Hemoglobin
Humans
Hyperglycemia
Images In
Insulin
Medical imaging
Older people
Patients
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Summary:The patient had recent admission 4 weeks ago with increased drowsiness and raised capillary blood glucose reading of 935 mg/dL with elevated serum osmolality level at 321 mosmol/kg and no ketoacidosis (pH 7.404), resulting in the diagnosis of hyperosmolar hyperglycaemic syndrome (HHS). Chorea may improve by glucose control in 25% of patients, while the majority may need treatment including GABA-receptor agonists, selective serotonin reuptake inhibitors and dopamine-depleting agents.9 New onset of ballism or chorea in a diabetic patient following HHS should alert the clinician about DS, which can be confirmed by MRI. Chorea may improve by glucose control in 25% of patients, while the majority may need treatment including GABA-receptor agonists, selective serotonin reuptake inhibitors and dopamine-depleting agents.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2021-244248