COVID-19 and mucormycosis in Latin America – An emerging concern

[...]its misuse could be an important factor in triggering aggressive mucormycosis in COVID-19 patients, as now observed worldwide. In that report, the case fatality rate (CFR) was 44% in men and 24% in women, while, due to underlying conditions, mortality was 45% in patients with diabetes mellitus;...

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Published in:Travel medicine and infectious disease 2021-11, Vol.44, p.102156-102156, Article 102156
Main Authors: Rodriguez-Morales, Alfonso J., Mamani-García, Carlos S., Nuñez-Lupaca, Janeth N., León-Figueroa, Darwin A., Olarte-Durand, Mely, Yrene-Cubas, Robinson A., Ticona, Diana M., Abanto-Urbano, Sebastian
Format: Article
Language:English
Subjects:
Comorbidity
Coronaviruses
Corticoids
COVID-19
Diabetes
Disease
Fatalities
Fungal infections
Humans
Hypertension
Infectious diseases
Latin America
Latin America - epidemiology
Men
Metabolism
Mortality
Mucormycosis
Mucormycosis - diagnosis
Mucormycosis - epidemiology
Pandemic
Pandemics
Patients
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Steroids
Surgery
Travel medicine
Ventilators
Viral infections
Women
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Summary:[...]its misuse could be an important factor in triggering aggressive mucormycosis in COVID-19 patients, as now observed worldwide. In that report, the case fatality rate (CFR) was 44% in men and 24% in women, while, due to underlying conditions, mortality was 45% in patients with diabetes mellitus; 37.9% in patients with burns or penetrating trauma; 58.5% in patients with immunosuppression, and 55.6% in patients who used corticosteroids. Mortality was observed in 30.7% of the cases. [...]a triad of diabetes mellitus, inappropriate use of corticosteroids and COVID-19 seems to increase mucormycosis cases. [...]every effort should be made to maintain optimal glucose and only the judicious use of corticosteroids in patients with COVID-19 [12].
ISSN:1477-8939
1873-0442
DOI:10.1016/j.tmaid.2021.102156