SARS-CoV-2-triggered lymphocytic colitis

The ability of SARS-CoV-2 to infect the gastrointestinal tract is well described. Inflammatory bowel diseases (IBD) are believed to represent a disorganised immune response in genetically predisposed individuals, which are triggered by various environmental factors, notably infections. Here we repor...

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Bibliographic Details
Published in:BMJ case reports 2021-08, Vol.14 (8), p.e243003
Main Authors: Nassar, Islam Osama, Langman, Gerald, Quraishi, Mohammed Nabil, Sharma, Naveen
Format: Article
Language:English
Subjects:
Biopsy
Case Report
Case reports
Colon
Colonoscopy
Coronaviruses
COVID-19
Diarrhea
Disease transmission
Fever
Gastroenteritis
Histology
Immunology
Infections
Inflammatory bowel disease
Patients
Rectum
Remission (Medicine)
Severe acute respiratory syndrome coronavirus 2
Thyroid gland
Viral infections
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Summary:The ability of SARS-CoV-2 to infect the gastrointestinal tract is well described. Inflammatory bowel diseases (IBD) are believed to represent a disorganised immune response in genetically predisposed individuals, which are triggered by various environmental factors, notably infections. Here we report a case of chronic watery diarrhoea that was triggered by a SARS-CoV-2 infection. The work-up confirmed a new diagnosis of lymphocytic colitis, and the patient responded favourably to a course of oral budesonide. Clinicians should become vigilant to the possibility of triggered IBD in patients with persistent diarrhoea following a SARS-CoV-2 infection.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2021-243003