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In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study
Objectives To study trends of utilization, outcomes, and cost of care in patients undergoing undergoing transcatheter mitral valve repair (TMVr) with end‐stage renal disease (ESRD). Background Renal disease has been known to be a predictor of poor outcome in patients with mitral valve disease. Outco...
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Published in: | Catheterization and cardiovascular interventions 2021-08, Vol.98 (2), p.343-351 |
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container_title | Catheterization and cardiovascular interventions |
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creator | Khan, Muhammad Zia Zahid, Salman Khan, Muhammad U. Kichloo, Asim Jamal, Shakeel Minhas, Abdul Mannan Khan Munir, Muhammad Bilal Balla, Sudarshan |
description | Objectives
To study trends of utilization, outcomes, and cost of care in patients undergoing undergoing transcatheter mitral valve repair (TMVr) with end‐stage renal disease (ESRD).
Background
Renal disease has been known to be a predictor of poor outcome in patients with mitral valve disease. Outcome data for patients with ESRD undergoing TMVr remains limited. Therefore, our study aims to investigate trends of utilization, outcomes, and cost of care among patients with ESRD undergoing TMVr.
Methods
We analyzed NIS data from January 2010 to December 2017 using the ICD‐9‐CM codes ICD‐10‐CM to identify patients who underwent TMVr. Baseline characteristics were compared using a Pearson χ2 test for categorical variables and independent samples t‐test for continuous variables. Propensity matched analysis was done for adjusted analysis to compare outcomes between TMVr with and without ESRD. Markov chain Monte Carlo was used to account for missing values.
Results
A total of 15,260 patients (weighted sample) undergoing TMVr were identified between 2010 and 2017. Of these, 638 patients had ESRD compared to 14,631 patients who did not have ESRD. Adjusted in‐hospital mortality was lower in non‐ESRD group (3.9 vs. |
doi_str_mv | 10.1002/ccd.29517 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8389075</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2559370997</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4437-83cd13e8463a48b8609aff2a75de778ba1ca39fc0058ab1701c336f3181c82763</originalsourceid><addsrcrecordid>eNp1kc-KFDEQxhtR3HX14AtIwIseZjfpdDqJB2EZ_y0seFHwFmrS1TtZupM2Sc8yNx9B8A19EjM746KCp3yp_OqjKl9VPWX0lFFan1nbndZaMHmvOmairheybr_cP2imm_aoepTSNaVUt7V-WB1xLmrZyva4-nHhf377vg5pchkGEuZsw4iJhJ7kCD5ZyGvMGMnoyn0gGxg2SCJO4CJxnkyQHfqcyI3LawK-uxXFhmDRKcPVjvals3MJIeErck58aQq72hTDhD65vCUjZLsuDXO3fVw96GFI-ORwnlSf3739tPywuPz4_mJ5frmwTcPlQnHbMY6qaTk0aqVaqqHva5CiQynVCpgFrntLqVCwYpIyy3nbc6aYVWV9flK93vtO82rEzpY9yopmim6EuDUBnPn7xbu1uQobo7jSVIpi8OJgEMPXGVM2o0sWhwE8hjmZulFCsJaLpqDP_0GvwxzLHxRKCM0l1VoW6uWesjGkFLG_G4ZRs4valKjNbdSFffbn9Hfk72wLcLYHbtyA2_87meXyzd7yF6GetzI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2559370997</pqid></control><display><type>article</type><title>In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study</title><source>Wiley</source><creator>Khan, Muhammad Zia ; Zahid, Salman ; Khan, Muhammad U. ; Kichloo, Asim ; Jamal, Shakeel ; Minhas, Abdul Mannan Khan ; Munir, Muhammad Bilal ; Balla, Sudarshan</creator><creatorcontrib>Khan, Muhammad Zia ; Zahid, Salman ; Khan, Muhammad U. ; Kichloo, Asim ; Jamal, Shakeel ; Minhas, Abdul Mannan Khan ; Munir, Muhammad Bilal ; Balla, Sudarshan</creatorcontrib><description>Objectives
To study trends of utilization, outcomes, and cost of care in patients undergoing undergoing transcatheter mitral valve repair (TMVr) with end‐stage renal disease (ESRD).
Background
Renal disease has been known to be a predictor of poor outcome in patients with mitral valve disease. Outcome data for patients with ESRD undergoing TMVr remains limited. Therefore, our study aims to investigate trends of utilization, outcomes, and cost of care among patients with ESRD undergoing TMVr.
Methods
We analyzed NIS data from January 2010 to December 2017 using the ICD‐9‐CM codes ICD‐10‐CM to identify patients who underwent TMVr. Baseline characteristics were compared using a Pearson χ2 test for categorical variables and independent samples t‐test for continuous variables. Propensity matched analysis was done for adjusted analysis to compare outcomes between TMVr with and without ESRD. Markov chain Monte Carlo was used to account for missing values.
Results
A total of 15,260 patients (weighted sample) undergoing TMVr were identified between 2010 and 2017. Of these, 638 patients had ESRD compared to 14,631 patients who did not have ESRD. Adjusted in‐hospital mortality was lower in non‐ESRD group (3.9 vs. <1.8%). Similarly, ESRD patients were more likely to have non‐home discharges (85.6 vs. 74.9%). ESRD patients also had a longer mean length of stay (7.9 vs. 13.5 days) and higher mean cost of stay ($306,300 vs. $271,503).
Conclusion
ESRD is associated with higher mortality, complications, and resource utilization compared to non‐ESRD patients. It is important to include this data in shared decision‐making process and patient selection.</description><identifier>ISSN: 1522-1946</identifier><identifier>ISSN: 1522-726X</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.29517</identifier><identifier>PMID: 33527676</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Cardiac Catheterization - adverse effects ; Decision making ; end‐stage renal disease ; Heart Valve Prosthesis Implantation - adverse effects ; Hospitals ; Humans ; Kidney diseases ; Kidney Failure, Chronic - diagnosis ; Kidney Failure, Chronic - therapy ; Markov chains ; Mitral valve ; Mitral Valve - diagnostic imaging ; Mitral Valve - surgery ; Mitral Valve Insufficiency - surgery ; Mortality ; Patients ; percutaneous edge‐to‐edge mitral valve repair ; percutaneous mitral valve repair with clip ; Resource utilization ; Rheumatic heart disease ; Treatment Outcome ; Trends</subject><ispartof>Catheterization and cardiovascular interventions, 2021-08, Vol.98 (2), p.343-351</ispartof><rights>2021 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4437-83cd13e8463a48b8609aff2a75de778ba1ca39fc0058ab1701c336f3181c82763</citedby><cites>FETCH-LOGICAL-c4437-83cd13e8463a48b8609aff2a75de778ba1ca39fc0058ab1701c336f3181c82763</cites><orcidid>0000-0002-9804-898X ; 0000-0002-4452-6317 ; 0000-0001-8473-8069</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33527676$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khan, Muhammad Zia</creatorcontrib><creatorcontrib>Zahid, Salman</creatorcontrib><creatorcontrib>Khan, Muhammad U.</creatorcontrib><creatorcontrib>Kichloo, Asim</creatorcontrib><creatorcontrib>Jamal, Shakeel</creatorcontrib><creatorcontrib>Minhas, Abdul Mannan Khan</creatorcontrib><creatorcontrib>Munir, Muhammad Bilal</creatorcontrib><creatorcontrib>Balla, Sudarshan</creatorcontrib><title>In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study</title><title>Catheterization and cardiovascular interventions</title><addtitle>Catheter Cardiovasc Interv</addtitle><description>Objectives
To study trends of utilization, outcomes, and cost of care in patients undergoing undergoing transcatheter mitral valve repair (TMVr) with end‐stage renal disease (ESRD).
Background
Renal disease has been known to be a predictor of poor outcome in patients with mitral valve disease. Outcome data for patients with ESRD undergoing TMVr remains limited. Therefore, our study aims to investigate trends of utilization, outcomes, and cost of care among patients with ESRD undergoing TMVr.
Methods
We analyzed NIS data from January 2010 to December 2017 using the ICD‐9‐CM codes ICD‐10‐CM to identify patients who underwent TMVr. Baseline characteristics were compared using a Pearson χ2 test for categorical variables and independent samples t‐test for continuous variables. Propensity matched analysis was done for adjusted analysis to compare outcomes between TMVr with and without ESRD. Markov chain Monte Carlo was used to account for missing values.
Results
A total of 15,260 patients (weighted sample) undergoing TMVr were identified between 2010 and 2017. Of these, 638 patients had ESRD compared to 14,631 patients who did not have ESRD. Adjusted in‐hospital mortality was lower in non‐ESRD group (3.9 vs. <1.8%). Similarly, ESRD patients were more likely to have non‐home discharges (85.6 vs. 74.9%). ESRD patients also had a longer mean length of stay (7.9 vs. 13.5 days) and higher mean cost of stay ($306,300 vs. $271,503).
Conclusion
ESRD is associated with higher mortality, complications, and resource utilization compared to non‐ESRD patients. It is important to include this data in shared decision‐making process and patient selection.</description><subject>Cardiac Catheterization - adverse effects</subject><subject>Decision making</subject><subject>end‐stage renal disease</subject><subject>Heart Valve Prosthesis Implantation - adverse effects</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Kidney diseases</subject><subject>Kidney Failure, Chronic - diagnosis</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Markov chains</subject><subject>Mitral valve</subject><subject>Mitral Valve - diagnostic imaging</subject><subject>Mitral Valve - surgery</subject><subject>Mitral Valve Insufficiency - surgery</subject><subject>Mortality</subject><subject>Patients</subject><subject>percutaneous edge‐to‐edge mitral valve repair</subject><subject>percutaneous mitral valve repair with clip</subject><subject>Resource utilization</subject><subject>Rheumatic heart disease</subject><subject>Treatment Outcome</subject><subject>Trends</subject><issn>1522-1946</issn><issn>1522-726X</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kc-KFDEQxhtR3HX14AtIwIseZjfpdDqJB2EZ_y0seFHwFmrS1TtZupM2Sc8yNx9B8A19EjM746KCp3yp_OqjKl9VPWX0lFFan1nbndZaMHmvOmairheybr_cP2imm_aoepTSNaVUt7V-WB1xLmrZyva4-nHhf377vg5pchkGEuZsw4iJhJ7kCD5ZyGvMGMnoyn0gGxg2SCJO4CJxnkyQHfqcyI3LawK-uxXFhmDRKcPVjvals3MJIeErck58aQq72hTDhD65vCUjZLsuDXO3fVw96GFI-ORwnlSf3739tPywuPz4_mJ5frmwTcPlQnHbMY6qaTk0aqVaqqHva5CiQynVCpgFrntLqVCwYpIyy3nbc6aYVWV9flK93vtO82rEzpY9yopmim6EuDUBnPn7xbu1uQobo7jSVIpi8OJgEMPXGVM2o0sWhwE8hjmZulFCsJaLpqDP_0GvwxzLHxRKCM0l1VoW6uWesjGkFLG_G4ZRs4valKjNbdSFffbn9Hfk72wLcLYHbtyA2_87meXyzd7yF6GetzI</recordid><startdate>20210801</startdate><enddate>20210801</enddate><creator>Khan, Muhammad Zia</creator><creator>Zahid, Salman</creator><creator>Khan, Muhammad U.</creator><creator>Kichloo, Asim</creator><creator>Jamal, Shakeel</creator><creator>Minhas, Abdul Mannan Khan</creator><creator>Munir, Muhammad Bilal</creator><creator>Balla, Sudarshan</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9804-898X</orcidid><orcidid>https://orcid.org/0000-0002-4452-6317</orcidid><orcidid>https://orcid.org/0000-0001-8473-8069</orcidid></search><sort><creationdate>20210801</creationdate><title>In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study</title><author>Khan, Muhammad Zia ; Zahid, Salman ; Khan, Muhammad U. ; Kichloo, Asim ; Jamal, Shakeel ; Minhas, Abdul Mannan Khan ; Munir, Muhammad Bilal ; Balla, Sudarshan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4437-83cd13e8463a48b8609aff2a75de778ba1ca39fc0058ab1701c336f3181c82763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Cardiac Catheterization - adverse effects</topic><topic>Decision making</topic><topic>end‐stage renal disease</topic><topic>Heart Valve Prosthesis Implantation - adverse effects</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Kidney diseases</topic><topic>Kidney Failure, Chronic - diagnosis</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Markov chains</topic><topic>Mitral valve</topic><topic>Mitral Valve - diagnostic imaging</topic><topic>Mitral Valve - surgery</topic><topic>Mitral Valve Insufficiency - surgery</topic><topic>Mortality</topic><topic>Patients</topic><topic>percutaneous edge‐to‐edge mitral valve repair</topic><topic>percutaneous mitral valve repair with clip</topic><topic>Resource utilization</topic><topic>Rheumatic heart disease</topic><topic>Treatment Outcome</topic><topic>Trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khan, Muhammad Zia</creatorcontrib><creatorcontrib>Zahid, Salman</creatorcontrib><creatorcontrib>Khan, Muhammad U.</creatorcontrib><creatorcontrib>Kichloo, Asim</creatorcontrib><creatorcontrib>Jamal, Shakeel</creatorcontrib><creatorcontrib>Minhas, Abdul Mannan Khan</creatorcontrib><creatorcontrib>Munir, Muhammad Bilal</creatorcontrib><creatorcontrib>Balla, Sudarshan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khan, Muhammad Zia</au><au>Zahid, Salman</au><au>Khan, Muhammad U.</au><au>Kichloo, Asim</au><au>Jamal, Shakeel</au><au>Minhas, Abdul Mannan Khan</au><au>Munir, Muhammad Bilal</au><au>Balla, Sudarshan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Catheter Cardiovasc Interv</addtitle><date>2021-08-01</date><risdate>2021</risdate><volume>98</volume><issue>2</issue><spage>343</spage><epage>351</epage><pages>343-351</pages><issn>1522-1946</issn><issn>1522-726X</issn><eissn>1522-726X</eissn><abstract>Objectives
To study trends of utilization, outcomes, and cost of care in patients undergoing undergoing transcatheter mitral valve repair (TMVr) with end‐stage renal disease (ESRD).
Background
Renal disease has been known to be a predictor of poor outcome in patients with mitral valve disease. Outcome data for patients with ESRD undergoing TMVr remains limited. Therefore, our study aims to investigate trends of utilization, outcomes, and cost of care among patients with ESRD undergoing TMVr.
Methods
We analyzed NIS data from January 2010 to December 2017 using the ICD‐9‐CM codes ICD‐10‐CM to identify patients who underwent TMVr. Baseline characteristics were compared using a Pearson χ2 test for categorical variables and independent samples t‐test for continuous variables. Propensity matched analysis was done for adjusted analysis to compare outcomes between TMVr with and without ESRD. Markov chain Monte Carlo was used to account for missing values.
Results
A total of 15,260 patients (weighted sample) undergoing TMVr were identified between 2010 and 2017. Of these, 638 patients had ESRD compared to 14,631 patients who did not have ESRD. Adjusted in‐hospital mortality was lower in non‐ESRD group (3.9 vs. <1.8%). Similarly, ESRD patients were more likely to have non‐home discharges (85.6 vs. 74.9%). ESRD patients also had a longer mean length of stay (7.9 vs. 13.5 days) and higher mean cost of stay ($306,300 vs. $271,503).
Conclusion
ESRD is associated with higher mortality, complications, and resource utilization compared to non‐ESRD patients. It is important to include this data in shared decision‐making process and patient selection.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>33527676</pmid><doi>10.1002/ccd.29517</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-9804-898X</orcidid><orcidid>https://orcid.org/0000-0002-4452-6317</orcidid><orcidid>https://orcid.org/0000-0001-8473-8069</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Cardiac Catheterization - adverse effects Decision making end‐stage renal disease Heart Valve Prosthesis Implantation - adverse effects Hospitals Humans Kidney diseases Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - therapy Markov chains Mitral valve Mitral Valve - diagnostic imaging Mitral Valve - surgery Mitral Valve Insufficiency - surgery Mortality Patients percutaneous edge‐to‐edge mitral valve repair percutaneous mitral valve repair with clip Resource utilization Rheumatic heart disease Treatment Outcome Trends |
title | In‐hospital outcomes of transcatheter mitral valve repair in patients with and without end stage renal disease: A national propensity match study |
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