Survival and Disease Recurrence in Patients with Duodenal Neuroendocrine Tumours—A Single Centre Cohort

Background: Duodenal neuroendocrine tumours (D-NETs) are rare but increasingly diagnosed. This study aimed to assess the overall survival and recurrence rate among patients treated for D-NETs. Methods: Patients with D-NETs were retrospectively reviewed with a median follow-up time of 4.8 years (rang...

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Bibliographic Details
Published in:Cancers 2021-08, Vol.13 (16), p.3985
Main Authors: Folkestad, Oddry, Wasmuth, Hans H., Mjønes, Patricia, Fougner, Reidun, Hauso, Øyvind, Fossmark, Reidar
Format: Article
Language:English
Subjects:
Abdomen
Archives & records
Biopsy
Cancer
Comorbidity
Disease
Endoscopy
Growth rate
Lymph nodes
Lymphatic system
Medical imaging
Medical records
Metastases
Metastasis
Neuroendocrine tumors
Patients
Small intestine
Surgery
Survival
Ulcers
Ultrasonic imaging
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Summary:Background: Duodenal neuroendocrine tumours (D-NETs) are rare but increasingly diagnosed. This study aimed to assess the overall survival and recurrence rate among patients treated for D-NETs. Methods: Patients with D-NETs were retrospectively reviewed with a median follow-up time of 4.8 years (range 0.0–17.2 years). Results: A total of 32 patients with median age 68.0 years were identified. Fifteen patients underwent surgery while ten patients underwent endoscopic treatment. Mean estimated overall survival for the entire population was 12.1 years (95% CI 9.5–14.7 years), while 5-year overall survival was 81.3%. Tumour grade G1 was associated with longer mean estimated survival compared to G2 tumours (13.2 years versus 4.4 years, p = 0.010). None of the 23 patients who underwent presumed radical endoscopic or surgical resection had disease recurrence during follow-up. Tumours
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers13163985