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Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar Spinal Arthrodesis
Background: To analyze gender differences regarding the recovery experience (pain, function, complications) after spinal arthrodesis surgery. Methods: Pre-operative and post-operative gender-based differences in patient-reported outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6...
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Published in: | Journal of clinical medicine 2021-08, Vol.10 (16), p.3654 |
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description | Background: To analyze gender differences regarding the recovery experience (pain, function, complications) after spinal arthrodesis surgery. Methods: Pre-operative and post-operative gender-based differences in patient-reported outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6 months, and 1 year were studied, including age, comorbidities, body mass index (BMI), diagnosis, number of vertebrae fused, type of surgery, primary vs. revision surgery, and complications. Statistical analysis included the use of Student’s t-test, Chi square, linear regression, Mann–Whitney U test, and Spearman’s rho. Results: Primary or revision posterior arthrodesis was performed on 1931 consecutive adults (1219 females, 712 males) for deformity and degenerative pathologies. At surgery, females were older than males (61.7 years vs. 59.7 years, p < 0.01), had slightly more comorbidities (1.75 vs. 1.5, p < 0.01), and were more likely to undergo deformity correction (38% vs. 22%, p < 0.01). Females described more pre-op pain (female VAS = 6.54 vs. male VAS = 6.41, p < 0.01) and lower pre-op function (female ODI = 49.73 vs. male ODI = 46.52, p < 0.01). By 3 months post-op, there was no significant gender difference in VAS or ODI scores. Similar pain and function scores between males and females continued through 6 months and 12 months. Conclusion: Although females have more pain and dysfunction before undergoing spinal surgery, the differences in these values do not reach the Minimum Clinically Important Difference (MCID). Post-operatively, there is no difference in pain and function scores among males and females at 3, 6, and 12 months. |
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Methods: Pre-operative and post-operative gender-based differences in patient-reported outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6 months, and 1 year were studied, including age, comorbidities, body mass index (BMI), diagnosis, number of vertebrae fused, type of surgery, primary vs. revision surgery, and complications. Statistical analysis included the use of Student’s t-test, Chi square, linear regression, Mann–Whitney U test, and Spearman’s rho. Results: Primary or revision posterior arthrodesis was performed on 1931 consecutive adults (1219 females, 712 males) for deformity and degenerative pathologies. At surgery, females were older than males (61.7 years vs. 59.7 years, p < 0.01), had slightly more comorbidities (1.75 vs. 1.5, p < 0.01), and were more likely to undergo deformity correction (38% vs. 22%, p < 0.01). Females described more pre-op pain (female VAS = 6.54 vs. male VAS = 6.41, p < 0.01) and lower pre-op function (female ODI = 49.73 vs. male ODI = 46.52, p < 0.01). By 3 months post-op, there was no significant gender difference in VAS or ODI scores. Similar pain and function scores between males and females continued through 6 months and 12 months. Conclusion: Although females have more pain and dysfunction before undergoing spinal surgery, the differences in these values do not reach the Minimum Clinically Important Difference (MCID). Post-operatively, there is no difference in pain and function scores among males and females at 3, 6, and 12 months.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm10163654</identifier><identifier>PMID: 34441952</identifier><language>eng</language><publisher>Basel: MDPI AG</publisher><subject>Age ; Back pain ; Back surgery ; Body mass index ; Clinical medicine ; Degenerative disc disease ; Females ; Gender differences ; Males ; Patients ; Physical therapy ; Regression analysis</subject><ispartof>Journal of clinical medicine, 2021-08, Vol.10 (16), p.3654</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-5cf76568bd0d89059cf832f28783a5cab63723946c281b7950311174a7c2bdea3</citedby><cites>FETCH-LOGICAL-c386t-5cf76568bd0d89059cf832f28783a5cab63723946c281b7950311174a7c2bdea3</cites><orcidid>0000-0003-3942-9595</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2565288950/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2565288950?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids></links><search><creatorcontrib>Gulbrandsen, Matthew T.</creatorcontrib><creatorcontrib>Lara, Nina</creatorcontrib><creatorcontrib>Beauchamp, James A.</creatorcontrib><creatorcontrib>Chung, Andrew</creatorcontrib><creatorcontrib>Chang, Michael</creatorcontrib><creatorcontrib>Crandall, Dennis</creatorcontrib><title>Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar Spinal Arthrodesis</title><title>Journal of clinical medicine</title><description>Background: To analyze gender differences regarding the recovery experience (pain, function, complications) after spinal arthrodesis surgery. Methods: Pre-operative and post-operative gender-based differences in patient-reported outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6 months, and 1 year were studied, including age, comorbidities, body mass index (BMI), diagnosis, number of vertebrae fused, type of surgery, primary vs. revision surgery, and complications. Statistical analysis included the use of Student’s t-test, Chi square, linear regression, Mann–Whitney U test, and Spearman’s rho. Results: Primary or revision posterior arthrodesis was performed on 1931 consecutive adults (1219 females, 712 males) for deformity and degenerative pathologies. At surgery, females were older than males (61.7 years vs. 59.7 years, p < 0.01), had slightly more comorbidities (1.75 vs. 1.5, p < 0.01), and were more likely to undergo deformity correction (38% vs. 22%, p < 0.01). Females described more pre-op pain (female VAS = 6.54 vs. male VAS = 6.41, p < 0.01) and lower pre-op function (female ODI = 49.73 vs. male ODI = 46.52, p < 0.01). By 3 months post-op, there was no significant gender difference in VAS or ODI scores. Similar pain and function scores between males and females continued through 6 months and 12 months. Conclusion: Although females have more pain and dysfunction before undergoing spinal surgery, the differences in these values do not reach the Minimum Clinically Important Difference (MCID). Post-operatively, there is no difference in pain and function scores among males and females at 3, 6, and 12 months.</description><subject>Age</subject><subject>Back pain</subject><subject>Back surgery</subject><subject>Body mass index</subject><subject>Clinical medicine</subject><subject>Degenerative disc disease</subject><subject>Females</subject><subject>Gender differences</subject><subject>Males</subject><subject>Patients</subject><subject>Physical therapy</subject><subject>Regression analysis</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNpdkU9LJDEQxYO4rDJ62i8Q8CLIaP4nfRFEHRUEF3f2HNLptJMhnYxJ98h8e3t0EHfrUFVQPx6veAD8wuic0gpdLG2HERZUcLYHDgmScoqoovvf9gNwXMoSjaUUI1j-BAeUMYYrTg6BvTU5bOCdi43L8Ma3rcsuWlegj_C3GZuJDZwN0fY-RRPgs7Np7fIGzlII6c3HFzhfpGxsCkNXmwz_rPyWu8r9IqfGFV-OwI_WhOKOd3MC_s5u59f308enu4frq8eppUr0U25bKbhQdYMaVSFe2VZR0hIlFTXcmlpQSWjFhCUK17LiiGKMJTPSkrpxhk7A5afuaqg711gX-2yCXmXfmbzRyXj97yX6hX5Ja61oJRFTo8DpTiCn18GVXne-WBeCiS4NRRMuBGKIczqiJ_-hyzTk8fEPihOltv4m4OyTsjmVkl37ZQYjvc1Pf8uPvgM-yIxM</recordid><startdate>20210818</startdate><enddate>20210818</enddate><creator>Gulbrandsen, Matthew T.</creator><creator>Lara, Nina</creator><creator>Beauchamp, James A.</creator><creator>Chung, Andrew</creator><creator>Chang, Michael</creator><creator>Crandall, Dennis</creator><general>MDPI AG</general><general>MDPI</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-3942-9595</orcidid></search><sort><creationdate>20210818</creationdate><title>Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar Spinal Arthrodesis</title><author>Gulbrandsen, Matthew T. ; Lara, Nina ; Beauchamp, James A. ; Chung, Andrew ; Chang, Michael ; Crandall, Dennis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-5cf76568bd0d89059cf832f28783a5cab63723946c281b7950311174a7c2bdea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Age</topic><topic>Back pain</topic><topic>Back surgery</topic><topic>Body mass index</topic><topic>Clinical medicine</topic><topic>Degenerative disc disease</topic><topic>Females</topic><topic>Gender differences</topic><topic>Males</topic><topic>Patients</topic><topic>Physical therapy</topic><topic>Regression analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gulbrandsen, Matthew T.</creatorcontrib><creatorcontrib>Lara, Nina</creatorcontrib><creatorcontrib>Beauchamp, James A.</creatorcontrib><creatorcontrib>Chung, Andrew</creatorcontrib><creatorcontrib>Chang, Michael</creatorcontrib><creatorcontrib>Crandall, Dennis</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest Publicly Available Content database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gulbrandsen, Matthew T.</au><au>Lara, Nina</au><au>Beauchamp, James A.</au><au>Chung, Andrew</au><au>Chang, Michael</au><au>Crandall, Dennis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar Spinal Arthrodesis</atitle><jtitle>Journal of clinical medicine</jtitle><date>2021-08-18</date><risdate>2021</risdate><volume>10</volume><issue>16</issue><spage>3654</spage><pages>3654-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>Background: To analyze gender differences regarding the recovery experience (pain, function, complications) after spinal arthrodesis surgery. Methods: Pre-operative and post-operative gender-based differences in patient-reported outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6 months, and 1 year were studied, including age, comorbidities, body mass index (BMI), diagnosis, number of vertebrae fused, type of surgery, primary vs. revision surgery, and complications. Statistical analysis included the use of Student’s t-test, Chi square, linear regression, Mann–Whitney U test, and Spearman’s rho. Results: Primary or revision posterior arthrodesis was performed on 1931 consecutive adults (1219 females, 712 males) for deformity and degenerative pathologies. At surgery, females were older than males (61.7 years vs. 59.7 years, p < 0.01), had slightly more comorbidities (1.75 vs. 1.5, p < 0.01), and were more likely to undergo deformity correction (38% vs. 22%, p < 0.01). Females described more pre-op pain (female VAS = 6.54 vs. male VAS = 6.41, p < 0.01) and lower pre-op function (female ODI = 49.73 vs. male ODI = 46.52, p < 0.01). By 3 months post-op, there was no significant gender difference in VAS or ODI scores. Similar pain and function scores between males and females continued through 6 months and 12 months. Conclusion: Although females have more pain and dysfunction before undergoing spinal surgery, the differences in these values do not reach the Minimum Clinically Important Difference (MCID). Post-operatively, there is no difference in pain and function scores among males and females at 3, 6, and 12 months.</abstract><cop>Basel</cop><pub>MDPI AG</pub><pmid>34441952</pmid><doi>10.3390/jcm10163654</doi><orcidid>https://orcid.org/0000-0003-3942-9595</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age Back pain Back surgery Body mass index Clinical medicine Degenerative disc disease Females Gender differences Males Patients Physical therapy Regression analysis |
title | Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar Spinal Arthrodesis |
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