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Preliminary Results of the “Capasquelet” Technique for Managing Femoral Bone Defects—Combining a Masquelet Induced Membrane and Capanna Vascularized Fibula with an Allograft

We describe the preliminary results of a novel two-stage reconstruction technique for extended femoral bone defects using an allograft in accordance with the Capanna technique with an embedded vascularized fibula graft in an induced membrane according to the Masquelet technique. We performed what we...

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Published in:Journal of personalized medicine 2021-08, Vol.11 (8), p.774
Main Authors: Combal, Alexis, Thuau, François, Fouasson-Chailloux, Alban, Arrigoni, Pierre-Paul, Baud’huin, Marc, Duteille, Franck, Crenn, Vincent
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container_title Journal of personalized medicine
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creator Combal, Alexis
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description We describe the preliminary results of a novel two-stage reconstruction technique for extended femoral bone defects using an allograft in accordance with the Capanna technique with an embedded vascularized fibula graft in an induced membrane according to the Masquelet technique. We performed what we refer to as “Capasquelet” surgery in femoral diaphyseal bone loss of at least 10 cm. Four patients were operated on using this technique: two tumors and two traumatic bone defects in a septic context with a minimum follow up of one year. Consolidation on both sides, when achieved, occurred at 5.5 months (4–7), with full weight-bearing at 11 weeks (8–12). The functional scores were satisfactory with an EQ5D of 63.3 (45–75). The time to bone union and early weight-bearing with this combined technique are promising compared to the literature. The osteoinductive role of the induced membrane could play a positive role in the evolution of the graft. Longer follow up and a larger cohort are needed to better assess the implications. Nonetheless, this two-stage technique appears to have ample promise, especially in a septic context or in adjuvant radiotherapy in an oncological context.
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subjects Antibiotics
Bone cancer
Bone loss
Bone surgery
Bone tumors
Defects
Femur
Fibula
Life Sciences
Medical imaging
Osteogenesis
Patients
Precision medicine
Radiation therapy
Skin & tissue grafts
Surgery
Surgical techniques
Tumors
Veins & arteries
X-rays
title Preliminary Results of the “Capasquelet” Technique for Managing Femoral Bone Defects—Combining a Masquelet Induced Membrane and Capanna Vascularized Fibula with an Allograft
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