Preconception and antenatal screening for the fragile site on the X‐chromosome

Preconception and antenatal screening for the fragile site on the X‐chromosome No strong evidence to show who, other than women at risk, should be screened before or during pregnancy for fragile X syndrome. Fragile X syndrome is caused by an inherited genetic defect that can result in mental disabil...

Full description

Saved in:
Bibliographic Details
Published in:Cochrane database of systematic reviews 2003-01, Vol.2003 (1)
Main Authors: Kornman, Louise H, Nisbet, Debbie L, Liebelt, Jan
Format: Article
Language:English
Subjects:
Developmental, psychosocial & learning problems
Fetal assessment before labour
Genetic disorders
Neurology
Pregnancy & childbirth
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3076-7aa6b57aed1b6637b5ae3c6d4cea801afb42fd5eb1738e9414a963241dcda44f3
cites
container_end_page
container_issue 1
container_start_page
container_title Cochrane database of systematic reviews
container_volume 2003
creator Kornman, Louise H
Nisbet, Debbie L
Liebelt, Jan
description Preconception and antenatal screening for the fragile site on the X‐chromosome No strong evidence to show who, other than women at risk, should be screened before or during pregnancy for fragile X syndrome. Fragile X syndrome is caused by an inherited genetic defect that can result in mental disability. There is no way of reversing the syndrome. Although it runs in families, many people do not realise they are carriers until they have an affected child. A blood test can identify whether a person is a carrier, and therefore whether a test on the unborn baby is worthwhile. Currently, only women who are thought to be more likely to pass on fragile X are offered testing before or during pregnancy. There are no trials to show whether offering the test to everyone is worthwhile.
doi_str_mv 10.1002/14651858.CD001806
format article
fullrecord <record><control><sourceid>pubmedcentral</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8407515</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>pubmedcentral_primary_oai_pubmedcentral_nih_gov_8407515</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3076-7aa6b57aed1b6637b5ae3c6d4cea801afb42fd5eb1738e9414a963241dcda44f3</originalsourceid><addsrcrecordid>eNpVjM9KAzEYxIMgtlYfwFteYGvS_N2LIFWrULAHhd6Wb5Nv28huUrKr4M1H8Bl9Elf04mFm4DfDEHLB2ZwztrjkUitulZ0vbxjjlukjMh1ZWchSbCfktO9fGBMl5_aETEbXpWZmSjabjC5Fh4chpEgh-lEDRhigpb3LiDHEHW1SpsMeaZNhF1qkfRiQjvsftv36-HT7nLrUpw7PyHEDbY_nfzkjz3e3T8v7Yv24elherwsnmNGFAdC1MoCe11oLUytA4bSXDsEyDk0tF41XWHMjLJaSSyi1WEjunQcpGzEjV7-_h9e6Q-8wDhna6pBDB_m9ShCq_00M-2qX3iormVFciW9hu16c</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Preconception and antenatal screening for the fragile site on the X‐chromosome</title><source>Alma/SFX Local Collection</source><creator>Kornman, Louise H ; Nisbet, Debbie L ; Liebelt, Jan</creator><creatorcontrib>Kornman, Louise H ; Nisbet, Debbie L ; Liebelt, Jan</creatorcontrib><description>Preconception and antenatal screening for the fragile site on the X‐chromosome No strong evidence to show who, other than women at risk, should be screened before or during pregnancy for fragile X syndrome. Fragile X syndrome is caused by an inherited genetic defect that can result in mental disability. There is no way of reversing the syndrome. Although it runs in families, many people do not realise they are carriers until they have an affected child. A blood test can identify whether a person is a carrier, and therefore whether a test on the unborn baby is worthwhile. Currently, only women who are thought to be more likely to pass on fragile X are offered testing before or during pregnancy. There are no trials to show whether offering the test to everyone is worthwhile.</description><identifier>EISSN: 1469-493X</identifier><identifier>DOI: 10.1002/14651858.CD001806</identifier><identifier>PMID: 11869607</identifier><language>eng</language><publisher>Chichester, UK: John Wiley &amp; Sons, Ltd</publisher><subject>Developmental, psychosocial &amp; learning problems ; Fetal assessment before labour ; Genetic disorders ; Neurology ; Pregnancy &amp; childbirth</subject><ispartof>Cochrane database of systematic reviews, 2003-01, Vol.2003 (1)</ispartof><rights>Copyright © 2010 The Cochrane Collaboration. Published by John Wiley &amp; Sons, Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3076-7aa6b57aed1b6637b5ae3c6d4cea801afb42fd5eb1738e9414a963241dcda44f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids></links><search><creatorcontrib>Kornman, Louise H</creatorcontrib><creatorcontrib>Nisbet, Debbie L</creatorcontrib><creatorcontrib>Liebelt, Jan</creatorcontrib><title>Preconception and antenatal screening for the fragile site on the X‐chromosome</title><title>Cochrane database of systematic reviews</title><description>Preconception and antenatal screening for the fragile site on the X‐chromosome No strong evidence to show who, other than women at risk, should be screened before or during pregnancy for fragile X syndrome. Fragile X syndrome is caused by an inherited genetic defect that can result in mental disability. There is no way of reversing the syndrome. Although it runs in families, many people do not realise they are carriers until they have an affected child. A blood test can identify whether a person is a carrier, and therefore whether a test on the unborn baby is worthwhile. Currently, only women who are thought to be more likely to pass on fragile X are offered testing before or during pregnancy. There are no trials to show whether offering the test to everyone is worthwhile.</description><subject>Developmental, psychosocial &amp; learning problems</subject><subject>Fetal assessment before labour</subject><subject>Genetic disorders</subject><subject>Neurology</subject><subject>Pregnancy &amp; childbirth</subject><issn>1469-493X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNpVjM9KAzEYxIMgtlYfwFteYGvS_N2LIFWrULAHhd6Wb5Nv28huUrKr4M1H8Bl9Elf04mFm4DfDEHLB2ZwztrjkUitulZ0vbxjjlukjMh1ZWchSbCfktO9fGBMl5_aETEbXpWZmSjabjC5Fh4chpEgh-lEDRhigpb3LiDHEHW1SpsMeaZNhF1qkfRiQjvsftv36-HT7nLrUpw7PyHEDbY_nfzkjz3e3T8v7Yv24elherwsnmNGFAdC1MoCe11oLUytA4bSXDsEyDk0tF41XWHMjLJaSSyi1WEjunQcpGzEjV7-_h9e6Q-8wDhna6pBDB_m9ShCq_00M-2qX3iormVFciW9hu16c</recordid><startdate>20030120</startdate><enddate>20030120</enddate><creator>Kornman, Louise H</creator><creator>Nisbet, Debbie L</creator><creator>Liebelt, Jan</creator><general>John Wiley &amp; Sons, Ltd</general><scope>5PM</scope></search><sort><creationdate>20030120</creationdate><title>Preconception and antenatal screening for the fragile site on the X‐chromosome</title><author>Kornman, Louise H ; Nisbet, Debbie L ; Liebelt, Jan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3076-7aa6b57aed1b6637b5ae3c6d4cea801afb42fd5eb1738e9414a963241dcda44f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Developmental, psychosocial &amp; learning problems</topic><topic>Fetal assessment before labour</topic><topic>Genetic disorders</topic><topic>Neurology</topic><topic>Pregnancy &amp; childbirth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kornman, Louise H</creatorcontrib><creatorcontrib>Nisbet, Debbie L</creatorcontrib><creatorcontrib>Liebelt, Jan</creatorcontrib><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cochrane database of systematic reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kornman, Louise H</au><au>Nisbet, Debbie L</au><au>Liebelt, Jan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preconception and antenatal screening for the fragile site on the X‐chromosome</atitle><jtitle>Cochrane database of systematic reviews</jtitle><date>2003-01-20</date><risdate>2003</risdate><volume>2003</volume><issue>1</issue><eissn>1469-493X</eissn><abstract>Preconception and antenatal screening for the fragile site on the X‐chromosome No strong evidence to show who, other than women at risk, should be screened before or during pregnancy for fragile X syndrome. Fragile X syndrome is caused by an inherited genetic defect that can result in mental disability. There is no way of reversing the syndrome. Although it runs in families, many people do not realise they are carriers until they have an affected child. A blood test can identify whether a person is a carrier, and therefore whether a test on the unborn baby is worthwhile. Currently, only women who are thought to be more likely to pass on fragile X are offered testing before or during pregnancy. There are no trials to show whether offering the test to everyone is worthwhile.</abstract><cop>Chichester, UK</cop><pub>John Wiley &amp; Sons, Ltd</pub><pmid>11869607</pmid><doi>10.1002/14651858.CD001806</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier EISSN: 1469-493X
ispartof Cochrane database of systematic reviews, 2003-01, Vol.2003 (1)
issn 1469-493X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8407515
source Alma/SFX Local Collection
subjects Developmental, psychosocial & learning problems
Fetal assessment before labour
Genetic disorders
Neurology
Pregnancy & childbirth
title Preconception and antenatal screening for the fragile site on the X‐chromosome
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T03%3A05%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmedcentral&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preconception%20and%20antenatal%20screening%20for%20the%20fragile%20site%20on%20the%20X%E2%80%90chromosome&rft.jtitle=Cochrane%20database%20of%20systematic%20reviews&rft.au=Kornman,%20Louise%20H&rft.date=2003-01-20&rft.volume=2003&rft.issue=1&rft.eissn=1469-493X&rft_id=info:doi/10.1002/14651858.CD001806&rft_dat=%3Cpubmedcentral%3Epubmedcentral_primary_oai_pubmedcentral_nih_gov_8407515%3C/pubmedcentral%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3076-7aa6b57aed1b6637b5ae3c6d4cea801afb42fd5eb1738e9414a963241dcda44f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/11869607&rfr_iscdi=true