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The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures

Purpose To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF). Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or pro...

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Published in:International orthopaedics 2021-12, Vol.45 (12), p.3025-3031
Main Authors: Bayrak, Alkan, Duramaz, Altuğ, Çakmur, Başar Burak, Kural, Cemal, Basaran, Serdar Hakan, Erçin, Ersin, Kural, Alev, Ursavaş, Hüseyin Tamer
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container_issue 12
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container_title International orthopaedics
container_volume 45
creator Bayrak, Alkan
Duramaz, Altuğ
Çakmur, Başar Burak
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Basaran, Serdar Hakan
Erçin, Ersin
Kural, Alev
Ursavaş, Hüseyin Tamer
description Purpose To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF). Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated. Results No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 ( p  = 0.016, p  = 0.012, p  = 0.031, and p  = 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods ( p  
doi_str_mv 10.1007/s00264-021-05201-3
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Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated. Results No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 ( p  = 0.016, p  = 0.012, p  = 0.031, and p  = 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods ( p  &lt; 0.05). Conclusion COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.</description><identifier>ISSN: 0341-2695</identifier><identifier>EISSN: 1432-5195</identifier><identifier>DOI: 10.1007/s00264-021-05201-3</identifier><identifier>PMID: 34471936</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Bone Nails ; COVID-19 ; Female ; Fracture Fixation, Intramedullary - adverse effects ; Hip Fractures - surgery ; Humans ; Male ; Medicine ; Medicine &amp; Public Health ; Original Paper ; Orthopedics ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome</subject><ispartof>International orthopaedics, 2021-12, Vol.45 (12), p.3025-3031</ispartof><rights>SICOT aisbl 2021</rights><rights>2021. 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Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated. Results No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 ( p  = 0.016, p  = 0.012, p  = 0.031, and p  = 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods ( p  &lt; 0.05). Conclusion COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.</description><subject>Bone Nails</subject><subject>COVID-19</subject><subject>Female</subject><subject>Fracture Fixation, Intramedullary - adverse effects</subject><subject>Hip Fractures - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Original Paper</subject><subject>Orthopedics</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>Treatment Outcome</subject><issn>0341-2695</issn><issn>1432-5195</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1DAUhSMEokPhBVggL9kE_Jcfb5DQQKFSpW4KW-uOY09cJfFw7UzJ2_Q5WPbJ6mFKBRtWtnTP-Y59T1G8ZvQdo7R5HynltSwpZyWtOGWleFKsmBS8rJiqnhYrKiQrea2qk-JFjNeUsqZu2fPiREjZMCXqVfHrqrfEOmdNIsGR9eX3808lU2QXok9-79NCwkT85AYYR0gBF7IDhNEmi5HA1JHUe0zL3W0HCxkDJhgOJoRkY_ZldfJ2SpGEvUUS_c88dH5v724XCxmRQ2FryY1PPYkzbr2BYVhIQpsJXSbkoITB9HC4eUMcgkkz2viyeOZgiPbVw3lafDv7fLX-Wl5cfjlff7wojZR1KkUDrGVGNrzuHFUbZ5RyzlUtFXk14JihG0WFEDUoaLikrqOm5cCF7DZN14jT4sORu5s3o-1M_g3CoHfoR8BFB_D638nke70Ne91Kqmp1ALx9AGD4MduY9OijscMAkw1z1Lyq20o1qq2ylB-lBkOMaN1jDKP6ULo-lq5z6fp36Vpk05u_H_ho-dNyFoijIObRtLWor8OMU17a_7D3RWC_lA</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Bayrak, Alkan</creator><creator>Duramaz, Altuğ</creator><creator>Çakmur, Başar Burak</creator><creator>Kural, Cemal</creator><creator>Basaran, Serdar Hakan</creator><creator>Erçin, Ersin</creator><creator>Kural, Alev</creator><creator>Ursavaş, Hüseyin Tamer</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9715-9530</orcidid><orcidid>https://orcid.org/0000-0002-3539-0972</orcidid><orcidid>https://orcid.org/0000-0002-2720-1975</orcidid><orcidid>https://orcid.org/0000-0001-7493-391X</orcidid><orcidid>https://orcid.org/0000-0003-0189-1645</orcidid><orcidid>https://orcid.org/0000-0002-5012-2079</orcidid><orcidid>https://orcid.org/0000-0003-0906-2083</orcidid><orcidid>https://orcid.org/0000-0003-1459-4316</orcidid></search><sort><creationdate>20211201</creationdate><title>The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures</title><author>Bayrak, Alkan ; 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Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated. Results No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 ( p  = 0.016, p  = 0.012, p  = 0.031, and p  = 0.011, respectively). 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source Springer Nature
subjects Bone Nails
COVID-19
Female
Fracture Fixation, Intramedullary - adverse effects
Hip Fractures - surgery
Humans
Male
Medicine
Medicine & Public Health
Original Paper
Orthopedics
Retrospective Studies
SARS-CoV-2
Treatment Outcome
title The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures
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