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The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures
Purpose To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF). Methods Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or pro...
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Published in: | International orthopaedics 2021-12, Vol.45 (12), p.3025-3031 |
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container_issue | 12 |
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container_title | International orthopaedics |
container_volume | 45 |
creator | Bayrak, Alkan Duramaz, Altuğ Çakmur, Başar Burak Kural, Cemal Basaran, Serdar Hakan Erçin, Ersin Kural, Alev Ursavaş, Hüseyin Tamer |
description | Purpose
To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF).
Methods
Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated.
Results
No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 (
p
= 0.016,
p
= 0.012,
p
= 0.031, and
p
= 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods (
p
|
doi_str_mv | 10.1007/s00264-021-05201-3 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409697</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2568597985</sourcerecordid><originalsourceid>FETCH-LOGICAL-c446t-37a181c4726df09bfc99fff5803269af1c0b903336a9a7240fd0c82a234db7d73</originalsourceid><addsrcrecordid>eNp9kc1u1DAUhSMEokPhBVggL9kE_Jcfb5DQQKFSpW4KW-uOY09cJfFw7UzJ2_Q5WPbJ6mFKBRtWtnTP-Y59T1G8ZvQdo7R5HynltSwpZyWtOGWleFKsmBS8rJiqnhYrKiQrea2qk-JFjNeUsqZu2fPiREjZMCXqVfHrqrfEOmdNIsGR9eX3808lU2QXok9-79NCwkT85AYYR0gBF7IDhNEmi5HA1JHUe0zL3W0HCxkDJhgOJoRkY_ZldfJ2SpGEvUUS_c88dH5v724XCxmRQ2FryY1PPYkzbr2BYVhIQpsJXSbkoITB9HC4eUMcgkkz2viyeOZgiPbVw3lafDv7fLX-Wl5cfjlff7wojZR1KkUDrGVGNrzuHFUbZ5RyzlUtFXk14JihG0WFEDUoaLikrqOm5cCF7DZN14jT4sORu5s3o-1M_g3CoHfoR8BFB_D638nke70Ne91Kqmp1ALx9AGD4MduY9OijscMAkw1z1Lyq20o1qq2ylB-lBkOMaN1jDKP6ULo-lq5z6fp36Vpk05u_H_ho-dNyFoijIObRtLWor8OMU17a_7D3RWC_lA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2568597985</pqid></control><display><type>article</type><title>The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures</title><source>Springer Nature</source><creator>Bayrak, Alkan ; Duramaz, Altuğ ; Çakmur, Başar Burak ; Kural, Cemal ; Basaran, Serdar Hakan ; Erçin, Ersin ; Kural, Alev ; Ursavaş, Hüseyin Tamer</creator><creatorcontrib>Bayrak, Alkan ; Duramaz, Altuğ ; Çakmur, Başar Burak ; Kural, Cemal ; Basaran, Serdar Hakan ; Erçin, Ersin ; Kural, Alev ; Ursavaş, Hüseyin Tamer</creatorcontrib><description>Purpose
To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF).
Methods
Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated.
Results
No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 (
p
= 0.016,
p
= 0.012,
p
= 0.031, and
p
= 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods (
p
< 0.05).
Conclusion
COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.</description><identifier>ISSN: 0341-2695</identifier><identifier>EISSN: 1432-5195</identifier><identifier>DOI: 10.1007/s00264-021-05201-3</identifier><identifier>PMID: 34471936</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Bone Nails ; COVID-19 ; Female ; Fracture Fixation, Intramedullary - adverse effects ; Hip Fractures - surgery ; Humans ; Male ; Medicine ; Medicine & Public Health ; Original Paper ; Orthopedics ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome</subject><ispartof>International orthopaedics, 2021-12, Vol.45 (12), p.3025-3031</ispartof><rights>SICOT aisbl 2021</rights><rights>2021. SICOT aisbl.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-37a181c4726df09bfc99fff5803269af1c0b903336a9a7240fd0c82a234db7d73</citedby><cites>FETCH-LOGICAL-c446t-37a181c4726df09bfc99fff5803269af1c0b903336a9a7240fd0c82a234db7d73</cites><orcidid>0000-0002-9715-9530 ; 0000-0002-3539-0972 ; 0000-0002-2720-1975 ; 0000-0001-7493-391X ; 0000-0003-0189-1645 ; 0000-0002-5012-2079 ; 0000-0003-0906-2083 ; 0000-0003-1459-4316</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34471936$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bayrak, Alkan</creatorcontrib><creatorcontrib>Duramaz, Altuğ</creatorcontrib><creatorcontrib>Çakmur, Başar Burak</creatorcontrib><creatorcontrib>Kural, Cemal</creatorcontrib><creatorcontrib>Basaran, Serdar Hakan</creatorcontrib><creatorcontrib>Erçin, Ersin</creatorcontrib><creatorcontrib>Kural, Alev</creatorcontrib><creatorcontrib>Ursavaş, Hüseyin Tamer</creatorcontrib><title>The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures</title><title>International orthopaedics</title><addtitle>International Orthopaedics (SICOT)</addtitle><addtitle>Int Orthop</addtitle><description>Purpose
To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF).
Methods
Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated.
Results
No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 (
p
= 0.016,
p
= 0.012,
p
= 0.031, and
p
= 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods (
p
< 0.05).
Conclusion
COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.</description><subject>Bone Nails</subject><subject>COVID-19</subject><subject>Female</subject><subject>Fracture Fixation, Intramedullary - adverse effects</subject><subject>Hip Fractures - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Paper</subject><subject>Orthopedics</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>Treatment Outcome</subject><issn>0341-2695</issn><issn>1432-5195</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1DAUhSMEokPhBVggL9kE_Jcfb5DQQKFSpW4KW-uOY09cJfFw7UzJ2_Q5WPbJ6mFKBRtWtnTP-Y59T1G8ZvQdo7R5HynltSwpZyWtOGWleFKsmBS8rJiqnhYrKiQrea2qk-JFjNeUsqZu2fPiREjZMCXqVfHrqrfEOmdNIsGR9eX3808lU2QXok9-79NCwkT85AYYR0gBF7IDhNEmi5HA1JHUe0zL3W0HCxkDJhgOJoRkY_ZldfJ2SpGEvUUS_c88dH5v724XCxmRQ2FryY1PPYkzbr2BYVhIQpsJXSbkoITB9HC4eUMcgkkz2viyeOZgiPbVw3lafDv7fLX-Wl5cfjlff7wojZR1KkUDrGVGNrzuHFUbZ5RyzlUtFXk14JihG0WFEDUoaLikrqOm5cCF7DZN14jT4sORu5s3o-1M_g3CoHfoR8BFB_D638nke70Ne91Kqmp1ALx9AGD4MduY9OijscMAkw1z1Lyq20o1qq2ylB-lBkOMaN1jDKP6ULo-lq5z6fp36Vpk05u_H_ho-dNyFoijIObRtLWor8OMU17a_7D3RWC_lA</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Bayrak, Alkan</creator><creator>Duramaz, Altuğ</creator><creator>Çakmur, Başar Burak</creator><creator>Kural, Cemal</creator><creator>Basaran, Serdar Hakan</creator><creator>Erçin, Ersin</creator><creator>Kural, Alev</creator><creator>Ursavaş, Hüseyin Tamer</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9715-9530</orcidid><orcidid>https://orcid.org/0000-0002-3539-0972</orcidid><orcidid>https://orcid.org/0000-0002-2720-1975</orcidid><orcidid>https://orcid.org/0000-0001-7493-391X</orcidid><orcidid>https://orcid.org/0000-0003-0189-1645</orcidid><orcidid>https://orcid.org/0000-0002-5012-2079</orcidid><orcidid>https://orcid.org/0000-0003-0906-2083</orcidid><orcidid>https://orcid.org/0000-0003-1459-4316</orcidid></search><sort><creationdate>20211201</creationdate><title>The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures</title><author>Bayrak, Alkan ; Duramaz, Altuğ ; Çakmur, Başar Burak ; Kural, Cemal ; Basaran, Serdar Hakan ; Erçin, Ersin ; Kural, Alev ; Ursavaş, Hüseyin Tamer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-37a181c4726df09bfc99fff5803269af1c0b903336a9a7240fd0c82a234db7d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Bone Nails</topic><topic>COVID-19</topic><topic>Female</topic><topic>Fracture Fixation, Intramedullary - adverse effects</topic><topic>Hip Fractures - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Paper</topic><topic>Orthopedics</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bayrak, Alkan</creatorcontrib><creatorcontrib>Duramaz, Altuğ</creatorcontrib><creatorcontrib>Çakmur, Başar Burak</creatorcontrib><creatorcontrib>Kural, Cemal</creatorcontrib><creatorcontrib>Basaran, Serdar Hakan</creatorcontrib><creatorcontrib>Erçin, Ersin</creatorcontrib><creatorcontrib>Kural, Alev</creatorcontrib><creatorcontrib>Ursavaş, Hüseyin Tamer</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International orthopaedics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bayrak, Alkan</au><au>Duramaz, Altuğ</au><au>Çakmur, Başar Burak</au><au>Kural, Cemal</au><au>Basaran, Serdar Hakan</au><au>Erçin, Ersin</au><au>Kural, Alev</au><au>Ursavaş, Hüseyin Tamer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures</atitle><jtitle>International orthopaedics</jtitle><stitle>International Orthopaedics (SICOT)</stitle><addtitle>Int Orthop</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>45</volume><issue>12</issue><spage>3025</spage><epage>3031</epage><pages>3025-3031</pages><issn>0341-2695</issn><eissn>1432-5195</eissn><abstract>Purpose
To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF).
Methods
Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated.
Results
No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 (
p
= 0.016,
p
= 0.012,
p
= 0.031, and
p
= 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods (
p
< 0.05).
Conclusion
COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34471936</pmid><doi>10.1007/s00264-021-05201-3</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9715-9530</orcidid><orcidid>https://orcid.org/0000-0002-3539-0972</orcidid><orcidid>https://orcid.org/0000-0002-2720-1975</orcidid><orcidid>https://orcid.org/0000-0001-7493-391X</orcidid><orcidid>https://orcid.org/0000-0003-0189-1645</orcidid><orcidid>https://orcid.org/0000-0002-5012-2079</orcidid><orcidid>https://orcid.org/0000-0003-0906-2083</orcidid><orcidid>https://orcid.org/0000-0003-1459-4316</orcidid><oa>free_for_read</oa></addata></record> |
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language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409697 |
source | Springer Nature |
subjects | Bone Nails COVID-19 Female Fracture Fixation, Intramedullary - adverse effects Hip Fractures - surgery Humans Male Medicine Medicine & Public Health Original Paper Orthopedics Retrospective Studies SARS-CoV-2 Treatment Outcome |
title | The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures |
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