Loading…
Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository
Purpose To report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens. Methods Beginning in December 2017, patients presenting for reproductive care at the University of Michigan were approached for s...
Saved in:
| Published in: | Journal of assisted reproduction and genetics 2021-08, Vol.38 (8), p.2097-2105 |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3 |
| container_end_page | 2105 |
| container_issue | 8 |
| container_start_page | 2097 |
| container_title | Journal of assisted reproduction and genetics |
| container_volume | 38 |
| creator | Schon, Samantha B. Raja, Nicholas Xu, Min Cameron, Heather Yang, Kun Reynolds, Jayne Fenner, Dee Marsh, Erica E. |
| description | Purpose
To report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens.
Methods
Beginning in December 2017, patients presenting for reproductive care at the University of Michigan were approached for study enrollment. Following consent, subjects completed detailed reproductive and health questionnaires. A variety of reproductive specimens and tissues were collected and processed for multiple downstream applications.
Results
Subject enrollment began in December of 2017. There are currently 1798 subjects enrolled. Female participants report a variety of reproductive disorders. Available samples include semen, sperm, follicular fluid, granulosa cells, immature oocytes, ovarian and uterine tissue, and blood samples.
Conclusion
We report the successful establishment of a reproductive registry and sample biorepository. Furthermore, we describe methods for collection and storage of a variety of reproductive tissue processed for multiple downstream translational applications. |
| doi_str_mv | 10.1007/s10815-021-02165-6 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8417183</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2568817731</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3</originalsourceid><addsrcrecordid>eNp9kc9u1DAQhyMEoqXwAhxQJC5cAnac2A4HJFSVP1IlLnC2bGe865U3Dh5nRV-GZ8XpLoVy4GDFznzzTZxfVT2n5DUlRLxBSiTtG9LSdfG-4Q-qc9oL1gjGyMOyJ71sSMflWfUEcUcIGWTLHldnjAnJC3Re_bzCrE3wuPXTptZ1gjnFcbHZH6A2PpZzRJ9juqldTLXR6G2tp7HOSU8YdPZx0qG0Iehkt29r-DFD8jBZqEc4QIjzKs5buK_GxezAZixvNx5z0a9S1Ps53JKnoU-rR04HhGen50X17cPV18tPzfWXj58v3183thNdbjhQNxLDHRVDy9pRi951Tg9dqWrJHcjR8NaQzgFzrHPDINwAhLhxGKwBzS6qd0fvvJg9jBamcr-g5uT3Ot2oqL26X5n8Vm3iQcmOCipZEbw6CVL8vgBmtfdoIQQ9QVxQtT0RnAsxrOjLf9BdXFL5iyvFpaRCMFqo9kjZFBETuLuPoUSt8atj_KpEr27jV7w0vfj7Gnctv_MuADsCWErTBtKf2f_R_gIQVsHv</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2568817731</pqid></control><display><type>article</type><title>Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository</title><source>PubMed (Medline)</source><source>Springer Link</source><creator>Schon, Samantha B. ; Raja, Nicholas ; Xu, Min ; Cameron, Heather ; Yang, Kun ; Reynolds, Jayne ; Fenner, Dee ; Marsh, Erica E.</creator><creatorcontrib>Schon, Samantha B. ; Raja, Nicholas ; Xu, Min ; Cameron, Heather ; Yang, Kun ; Reynolds, Jayne ; Fenner, Dee ; Marsh, Erica E.</creatorcontrib><description>Purpose
To report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens.
Methods
Beginning in December 2017, patients presenting for reproductive care at the University of Michigan were approached for study enrollment. Following consent, subjects completed detailed reproductive and health questionnaires. A variety of reproductive specimens and tissues were collected and processed for multiple downstream applications.
Results
Subject enrollment began in December of 2017. There are currently 1798 subjects enrolled. Female participants report a variety of reproductive disorders. Available samples include semen, sperm, follicular fluid, granulosa cells, immature oocytes, ovarian and uterine tissue, and blood samples.
Conclusion
We report the successful establishment of a reproductive registry and sample biorepository. Furthermore, we describe methods for collection and storage of a variety of reproductive tissue processed for multiple downstream translational applications.</description><identifier>ISSN: 1058-0468</identifier><identifier>EISSN: 1573-7330</identifier><identifier>DOI: 10.1007/s10815-021-02165-6</identifier><identifier>PMID: 33786733</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biobanks ; Consent ; Data collection ; Endocrinology ; Enrollments ; Female ; Fertility ; Follicular fluid ; Granulosa cells ; Gynecology ; Health care ; Human Genetics ; Humans ; In vitro fertilization ; Infertility ; Initiatives ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Obstetrics ; Oocytes ; Pathophysiology ; Patients ; Phlebotomy ; Precision medicine ; Registries - statistics & numerical data ; Reproduction ; Reproductive health ; Reproductive Medicine ; Reproductive Physiology and Disease ; Specimen Handling - methods ; Surgery ; Surveys and Questionnaires ; Tissue Banks - organization & administration ; Tissue Banks - statistics & numerical data ; Translation ; Translational Research, Biomedical - standards ; Urine ; Uterus ; Young Adult</subject><ispartof>Journal of assisted reproduction and genetics, 2021-08, Vol.38 (8), p.2097-2105</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3</citedby><cites>FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3</cites><orcidid>0000-0001-5524-3649</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417183/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417183/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33786733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schon, Samantha B.</creatorcontrib><creatorcontrib>Raja, Nicholas</creatorcontrib><creatorcontrib>Xu, Min</creatorcontrib><creatorcontrib>Cameron, Heather</creatorcontrib><creatorcontrib>Yang, Kun</creatorcontrib><creatorcontrib>Reynolds, Jayne</creatorcontrib><creatorcontrib>Fenner, Dee</creatorcontrib><creatorcontrib>Marsh, Erica E.</creatorcontrib><title>Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository</title><title>Journal of assisted reproduction and genetics</title><addtitle>J Assist Reprod Genet</addtitle><addtitle>J Assist Reprod Genet</addtitle><description>Purpose
To report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens.
Methods
Beginning in December 2017, patients presenting for reproductive care at the University of Michigan were approached for study enrollment. Following consent, subjects completed detailed reproductive and health questionnaires. A variety of reproductive specimens and tissues were collected and processed for multiple downstream applications.
Results
Subject enrollment began in December of 2017. There are currently 1798 subjects enrolled. Female participants report a variety of reproductive disorders. Available samples include semen, sperm, follicular fluid, granulosa cells, immature oocytes, ovarian and uterine tissue, and blood samples.
Conclusion
We report the successful establishment of a reproductive registry and sample biorepository. Furthermore, we describe methods for collection and storage of a variety of reproductive tissue processed for multiple downstream translational applications.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biobanks</subject><subject>Consent</subject><subject>Data collection</subject><subject>Endocrinology</subject><subject>Enrollments</subject><subject>Female</subject><subject>Fertility</subject><subject>Follicular fluid</subject><subject>Granulosa cells</subject><subject>Gynecology</subject><subject>Health care</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>In vitro fertilization</subject><subject>Infertility</subject><subject>Initiatives</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Obstetrics</subject><subject>Oocytes</subject><subject>Pathophysiology</subject><subject>Patients</subject><subject>Phlebotomy</subject><subject>Precision medicine</subject><subject>Registries - statistics & numerical data</subject><subject>Reproduction</subject><subject>Reproductive health</subject><subject>Reproductive Medicine</subject><subject>Reproductive Physiology and Disease</subject><subject>Specimen Handling - methods</subject><subject>Surgery</subject><subject>Surveys and Questionnaires</subject><subject>Tissue Banks - organization & administration</subject><subject>Tissue Banks - statistics & numerical data</subject><subject>Translation</subject><subject>Translational Research, Biomedical - standards</subject><subject>Urine</subject><subject>Uterus</subject><subject>Young Adult</subject><issn>1058-0468</issn><issn>1573-7330</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kc9u1DAQhyMEoqXwAhxQJC5cAnac2A4HJFSVP1IlLnC2bGe865U3Dh5nRV-GZ8XpLoVy4GDFznzzTZxfVT2n5DUlRLxBSiTtG9LSdfG-4Q-qc9oL1gjGyMOyJ71sSMflWfUEcUcIGWTLHldnjAnJC3Re_bzCrE3wuPXTptZ1gjnFcbHZH6A2PpZzRJ9juqldTLXR6G2tp7HOSU8YdPZx0qG0Iehkt29r-DFD8jBZqEc4QIjzKs5buK_GxezAZixvNx5z0a9S1Ps53JKnoU-rR04HhGen50X17cPV18tPzfWXj58v3183thNdbjhQNxLDHRVDy9pRi951Tg9dqWrJHcjR8NaQzgFzrHPDINwAhLhxGKwBzS6qd0fvvJg9jBamcr-g5uT3Ot2oqL26X5n8Vm3iQcmOCipZEbw6CVL8vgBmtfdoIQQ9QVxQtT0RnAsxrOjLf9BdXFL5iyvFpaRCMFqo9kjZFBETuLuPoUSt8atj_KpEr27jV7w0vfj7Gnctv_MuADsCWErTBtKf2f_R_gIQVsHv</recordid><startdate>20210801</startdate><enddate>20210801</enddate><creator>Schon, Samantha B.</creator><creator>Raja, Nicholas</creator><creator>Xu, Min</creator><creator>Cameron, Heather</creator><creator>Yang, Kun</creator><creator>Reynolds, Jayne</creator><creator>Fenner, Dee</creator><creator>Marsh, Erica E.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5524-3649</orcidid></search><sort><creationdate>20210801</creationdate><title>Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository</title><author>Schon, Samantha B. ; Raja, Nicholas ; Xu, Min ; Cameron, Heather ; Yang, Kun ; Reynolds, Jayne ; Fenner, Dee ; Marsh, Erica E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biobanks</topic><topic>Consent</topic><topic>Data collection</topic><topic>Endocrinology</topic><topic>Enrollments</topic><topic>Female</topic><topic>Fertility</topic><topic>Follicular fluid</topic><topic>Granulosa cells</topic><topic>Gynecology</topic><topic>Health care</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>In vitro fertilization</topic><topic>Infertility</topic><topic>Initiatives</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Obstetrics</topic><topic>Oocytes</topic><topic>Pathophysiology</topic><topic>Patients</topic><topic>Phlebotomy</topic><topic>Precision medicine</topic><topic>Registries - statistics & numerical data</topic><topic>Reproduction</topic><topic>Reproductive health</topic><topic>Reproductive Medicine</topic><topic>Reproductive Physiology and Disease</topic><topic>Specimen Handling - methods</topic><topic>Surgery</topic><topic>Surveys and Questionnaires</topic><topic>Tissue Banks - organization & administration</topic><topic>Tissue Banks - statistics & numerical data</topic><topic>Translation</topic><topic>Translational Research, Biomedical - standards</topic><topic>Urine</topic><topic>Uterus</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schon, Samantha B.</creatorcontrib><creatorcontrib>Raja, Nicholas</creatorcontrib><creatorcontrib>Xu, Min</creatorcontrib><creatorcontrib>Cameron, Heather</creatorcontrib><creatorcontrib>Yang, Kun</creatorcontrib><creatorcontrib>Reynolds, Jayne</creatorcontrib><creatorcontrib>Fenner, Dee</creatorcontrib><creatorcontrib>Marsh, Erica E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of assisted reproduction and genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schon, Samantha B.</au><au>Raja, Nicholas</au><au>Xu, Min</au><au>Cameron, Heather</au><au>Yang, Kun</au><au>Reynolds, Jayne</au><au>Fenner, Dee</au><au>Marsh, Erica E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository</atitle><jtitle>Journal of assisted reproduction and genetics</jtitle><stitle>J Assist Reprod Genet</stitle><addtitle>J Assist Reprod Genet</addtitle><date>2021-08-01</date><risdate>2021</risdate><volume>38</volume><issue>8</issue><spage>2097</spage><epage>2105</epage><pages>2097-2105</pages><issn>1058-0468</issn><eissn>1573-7330</eissn><abstract>Purpose
To report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens.
Methods
Beginning in December 2017, patients presenting for reproductive care at the University of Michigan were approached for study enrollment. Following consent, subjects completed detailed reproductive and health questionnaires. A variety of reproductive specimens and tissues were collected and processed for multiple downstream applications.
Results
Subject enrollment began in December of 2017. There are currently 1798 subjects enrolled. Female participants report a variety of reproductive disorders. Available samples include semen, sperm, follicular fluid, granulosa cells, immature oocytes, ovarian and uterine tissue, and blood samples.
Conclusion
We report the successful establishment of a reproductive registry and sample biorepository. Furthermore, we describe methods for collection and storage of a variety of reproductive tissue processed for multiple downstream translational applications.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33786733</pmid><doi>10.1007/s10815-021-02165-6</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-5524-3649</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-0468 |
| ispartof | Journal of assisted reproduction and genetics, 2021-08, Vol.38 (8), p.2097-2105 |
| issn | 1058-0468 1573-7330 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8417183 |
| source | PubMed (Medline); Springer Link |
| subjects | Adolescent Adult Aged Aged, 80 and over Biobanks Consent Data collection Endocrinology Enrollments Female Fertility Follicular fluid Granulosa cells Gynecology Health care Human Genetics Humans In vitro fertilization Infertility Initiatives Male Medicine Medicine & Public Health Middle Aged Obstetrics Oocytes Pathophysiology Patients Phlebotomy Precision medicine Registries - statistics & numerical data Reproduction Reproductive health Reproductive Medicine Reproductive Physiology and Disease Specimen Handling - methods Surgery Surveys and Questionnaires Tissue Banks - organization & administration Tissue Banks - statistics & numerical data Translation Translational Research, Biomedical - standards Urine Uterus Young Adult |
| title | Establishing a reproductive biorepository for basic and translational research: experience developing the reproductive subjects registry and sample repository |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T01%3A04%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Establishing%20a%20reproductive%20biorepository%20for%20basic%20and%20translational%20research:%20experience%20developing%20the%20reproductive%20subjects%20registry%20and%20sample%20repository&rft.jtitle=Journal%20of%20assisted%20reproduction%20and%20genetics&rft.au=Schon,%20Samantha%20B.&rft.date=2021-08-01&rft.volume=38&rft.issue=8&rft.spage=2097&rft.epage=2105&rft.pages=2097-2105&rft.issn=1058-0468&rft.eissn=1573-7330&rft_id=info:doi/10.1007/s10815-021-02165-6&rft_dat=%3Cproquest_pubme%3E2568817731%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c474t-6e1fd0b6f179232da75f4fa94474a86fe8db62b04fe3f34f997f9e00fd99cbea3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2568817731&rft_id=info:pmid/33786733&rfr_iscdi=true |