Pathogenesis of autoimmune hepatitis

Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and d...

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Published in:World journal of hepatology 2021-08, Vol.13 (8), p.879-886
Main Authors: Fan, Jun-Hua, Liu, Geng-Feng, Lv, Xiao-Dan, Zeng, Rui-Zhi, Zhan, Ling-Ling, Lv, Xiao-Ping
Format: Article
Language:English
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Summary:Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and drugs that may cause immune dysfunction. This article reviews the pathogenesis of AIH and describes the latest research results in the past 5 years.
ISSN:1948-5182
1948-5182
DOI:10.4254/wjh.v13.i8.879