Loading…

Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models

Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is a...

Full description

Saved in:
Bibliographic Details
Published in:Journal of mathematical biology 2021-10, Vol.83 (4), p.34-34, Article 34
Main Authors: Calleri, Fabiana, Nastasi, Giovanni, Romano, Vittorio
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213
cites cdi_FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213
container_end_page 34
container_issue 4
container_start_page 34
container_title Journal of mathematical biology
container_volume 83
creator Calleri, Fabiana
Nastasi, Giovanni
Romano, Vittorio
description Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class A of asymptomatic individuals and the class L of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.
doi_str_mv 10.1007/s00285-021-01657-4
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8439375</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2572354652</sourcerecordid><originalsourceid>FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</originalsourceid><addsrcrecordid>eNp9kc1u1TAQRiMEopfCC7CyxIaNi8c_SbxBQrdQKhV1A2wtx5k0rpI42E4RD8L74t5bgWDByos537HHX1W9BHYGjDVvEmO8VZRxoAxq1VD5qNqBFJyChPpxtWOCCVq3wE-qZyndMgaN0vC0OhFSca613FU_92HJftnClmj2M5KUgxttyt6RNQaHKWEiQ4gkj2W4RrQ9CQPZX3-9PKegSe8T2lRGft4mm7End94SSz4VL5K9jVMgdi0q60Zil564MK82-hQW8t3nkfSYMc5-8Yc759DjlJ5XTwY7JXzxcJ5WXz68_7z_SK-uLy73766okwoyFQPTjRs6xlroG9BKaXSgNGtlbzvkrJPMalAom2FQnZLQANTWdVoLhhzEafX26F23bsbe4ZKjncwa_WzjDxOsN39PFj-am3BnWim0aFQRvH4QxPBtw5TN7JPDabILli81XDX8Hmx1QV_9g96GLS5lvQMllKwVLxQ_Ui6GlCIOvx8DzNy3bo6tm9K6ObRuZAmJY6j045cbjH_U_0n9Avj8sGY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2572354652</pqid></control><display><type>article</type><title>Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models</title><source>Springer Nature</source><creator>Calleri, Fabiana ; Nastasi, Giovanni ; Romano, Vittorio</creator><creatorcontrib>Calleri, Fabiana ; Nastasi, Giovanni ; Romano, Vittorio</creatorcontrib><description>Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class A of asymptomatic individuals and the class L of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.</description><identifier>ISSN: 0303-6812</identifier><identifier>EISSN: 1432-1416</identifier><identifier>DOI: 10.1007/s00285-021-01657-4</identifier><identifier>PMID: 34522994</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Applications of Mathematics ; Compartments ; Coronaviruses ; COVID-19 ; Differential equations ; Disease control ; Herd immunity ; Mathematical and Computational Biology ; Mathematics ; Mathematics and Statistics ; Ordinary differential equations ; Pandemics ; Stochastic models ; Stochastic processes ; Viral diseases</subject><ispartof>Journal of mathematical biology, 2021-10, Vol.83 (4), p.34-34, Article 34</ispartof><rights>The Author(s) 2021</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</citedby><cites>FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</cites><orcidid>0000-0002-2967-6552</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,778,782,883,27911,27912</link.rule.ids></links><search><creatorcontrib>Calleri, Fabiana</creatorcontrib><creatorcontrib>Nastasi, Giovanni</creatorcontrib><creatorcontrib>Romano, Vittorio</creatorcontrib><title>Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models</title><title>Journal of mathematical biology</title><addtitle>J. Math. Biol</addtitle><description>Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class A of asymptomatic individuals and the class L of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.</description><subject>Applications of Mathematics</subject><subject>Compartments</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Differential equations</subject><subject>Disease control</subject><subject>Herd immunity</subject><subject>Mathematical and Computational Biology</subject><subject>Mathematics</subject><subject>Mathematics and Statistics</subject><subject>Ordinary differential equations</subject><subject>Pandemics</subject><subject>Stochastic models</subject><subject>Stochastic processes</subject><subject>Viral diseases</subject><issn>0303-6812</issn><issn>1432-1416</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1TAQRiMEopfCC7CyxIaNi8c_SbxBQrdQKhV1A2wtx5k0rpI42E4RD8L74t5bgWDByos537HHX1W9BHYGjDVvEmO8VZRxoAxq1VD5qNqBFJyChPpxtWOCCVq3wE-qZyndMgaN0vC0OhFSca613FU_92HJftnClmj2M5KUgxttyt6RNQaHKWEiQ4gkj2W4RrQ9CQPZX3-9PKegSe8T2lRGft4mm7End94SSz4VL5K9jVMgdi0q60Zil564MK82-hQW8t3nkfSYMc5-8Yc759DjlJ5XTwY7JXzxcJ5WXz68_7z_SK-uLy73766okwoyFQPTjRs6xlroG9BKaXSgNGtlbzvkrJPMalAom2FQnZLQANTWdVoLhhzEafX26F23bsbe4ZKjncwa_WzjDxOsN39PFj-am3BnWim0aFQRvH4QxPBtw5TN7JPDabILli81XDX8Hmx1QV_9g96GLS5lvQMllKwVLxQ_Ui6GlCIOvx8DzNy3bo6tm9K6ObRuZAmJY6j045cbjH_U_0n9Avj8sGY</recordid><startdate>20211001</startdate><enddate>20211001</enddate><creator>Calleri, Fabiana</creator><creator>Nastasi, Giovanni</creator><creator>Romano, Vittorio</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>M7Z</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2967-6552</orcidid></search><sort><creationdate>20211001</creationdate><title>Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models</title><author>Calleri, Fabiana ; Nastasi, Giovanni ; Romano, Vittorio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Applications of Mathematics</topic><topic>Compartments</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Differential equations</topic><topic>Disease control</topic><topic>Herd immunity</topic><topic>Mathematical and Computational Biology</topic><topic>Mathematics</topic><topic>Mathematics and Statistics</topic><topic>Ordinary differential equations</topic><topic>Pandemics</topic><topic>Stochastic models</topic><topic>Stochastic processes</topic><topic>Viral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Calleri, Fabiana</creatorcontrib><creatorcontrib>Nastasi, Giovanni</creatorcontrib><creatorcontrib>Romano, Vittorio</creatorcontrib><collection>SpringerOpen</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Computer Science Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of mathematical biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Calleri, Fabiana</au><au>Nastasi, Giovanni</au><au>Romano, Vittorio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models</atitle><jtitle>Journal of mathematical biology</jtitle><stitle>J. Math. Biol</stitle><date>2021-10-01</date><risdate>2021</risdate><volume>83</volume><issue>4</issue><spage>34</spage><epage>34</epage><pages>34-34</pages><artnum>34</artnum><issn>0303-6812</issn><eissn>1432-1416</eissn><abstract>Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class A of asymptomatic individuals and the class L of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34522994</pmid><doi>10.1007/s00285-021-01657-4</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-2967-6552</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0303-6812
ispartof Journal of mathematical biology, 2021-10, Vol.83 (4), p.34-34, Article 34
issn 0303-6812
1432-1416
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8439375
source Springer Nature
subjects Applications of Mathematics
Compartments
Coronaviruses
COVID-19
Differential equations
Disease control
Herd immunity
Mathematical and Computational Biology
Mathematics
Mathematics and Statistics
Ordinary differential equations
Pandemics
Stochastic models
Stochastic processes
Viral diseases
title Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T09%3A30%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Continuous-time%20stochastic%20processes%20for%20the%20spread%20of%20COVID-19%20disease%20simulated%20via%20a%20Monte%20Carlo%20approach%20and%20comparison%20with%20deterministic%20models&rft.jtitle=Journal%20of%20mathematical%20biology&rft.au=Calleri,%20Fabiana&rft.date=2021-10-01&rft.volume=83&rft.issue=4&rft.spage=34&rft.epage=34&rft.pages=34-34&rft.artnum=34&rft.issn=0303-6812&rft.eissn=1432-1416&rft_id=info:doi/10.1007/s00285-021-01657-4&rft_dat=%3Cproquest_pubme%3E2572354652%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2572354652&rft_id=info:pmid/34522994&rfr_iscdi=true