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Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models
Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible S , infected I , removed R and dead people D . In order to have a cross validation, a deterministic version of such a model is a...
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Published in: | Journal of mathematical biology 2021-10, Vol.83 (4), p.34-34, Article 34 |
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creator | Calleri, Fabiana Nastasi, Giovanni Romano, Vittorio |
description | Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible
S
, infected
I
, removed
R
and dead people
D
. In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class
A
of asymptomatic individuals and the class
L
of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy. |
doi_str_mv | 10.1007/s00285-021-01657-4 |
format | article |
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S
, infected
I
, removed
R
and dead people
D
. In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class
A
of asymptomatic individuals and the class
L
of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.</description><identifier>ISSN: 0303-6812</identifier><identifier>EISSN: 1432-1416</identifier><identifier>DOI: 10.1007/s00285-021-01657-4</identifier><identifier>PMID: 34522994</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Applications of Mathematics ; Compartments ; Coronaviruses ; COVID-19 ; Differential equations ; Disease control ; Herd immunity ; Mathematical and Computational Biology ; Mathematics ; Mathematics and Statistics ; Ordinary differential equations ; Pandemics ; Stochastic models ; Stochastic processes ; Viral diseases</subject><ispartof>Journal of mathematical biology, 2021-10, Vol.83 (4), p.34-34, Article 34</ispartof><rights>The Author(s) 2021</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</citedby><cites>FETCH-LOGICAL-c451t-3f097cfb0081d719559ec159084dabe20b40a915e47ff5b5417116acb9930e213</cites><orcidid>0000-0002-2967-6552</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,778,782,883,27911,27912</link.rule.ids></links><search><creatorcontrib>Calleri, Fabiana</creatorcontrib><creatorcontrib>Nastasi, Giovanni</creatorcontrib><creatorcontrib>Romano, Vittorio</creatorcontrib><title>Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models</title><title>Journal of mathematical biology</title><addtitle>J. Math. Biol</addtitle><description>Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible
S
, infected
I
, removed
R
and dead people
D
. In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class
A
of asymptomatic individuals and the class
L
of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. 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S
, infected
I
, removed
R
and dead people
D
. In order to have a cross validation, a deterministic version of such a model is also devised which is represented by a system of ordinary differential equations with delays. In the second stochastic model two further compartments are added: the class
A
of asymptomatic individuals and the class
L
of isolated infected people. Effects such as social distancing measures are easily included and the consequences are analyzed. Numerical solutions are obtained with Monte Carlo simulations. Quantitative predictions are provided which can be useful for the evaluation of political measures, e.g. the obtained results suggest that strategies based on herd immunity are too risky. Finally, the models are calibrated on data referring to the second wave of infection in Italy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34522994</pmid><doi>10.1007/s00285-021-01657-4</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-2967-6552</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Applications of Mathematics Compartments Coronaviruses COVID-19 Differential equations Disease control Herd immunity Mathematical and Computational Biology Mathematics Mathematics and Statistics Ordinary differential equations Pandemics Stochastic models Stochastic processes Viral diseases |
title | Continuous-time stochastic processes for the spread of COVID-19 disease simulated via a Monte Carlo approach and comparison with deterministic models |
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