Neonatal Exposure to Tramadol through Mother’s Breast Milk

Abstract Tramadol is an opioid used in the treatment of moderate to moderately severe pain. Tramadol’s use during pregnancy is generally avoided and may cause some reversible withdrawal effects in neonates, and its use during lactation is not licensed by the manufacturer. A small clinical trial repo...

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Published in:Journal of analytical toxicology 2021-10, Vol.45 (8), p.840-846
Main Authors: Gesseck, Ashley M, Peace, Michelle R, Nanco, Carrol R, Wolf, Carl E, Hendricks-Muñoz, Karen D, Xu, Jie, Poklis, Justin L
Format: Article
Language:English
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Summary:Abstract Tramadol is an opioid used in the treatment of moderate to moderately severe pain. Tramadol’s use during pregnancy is generally avoided and may cause some reversible withdrawal effects in neonates, and its use during lactation is not licensed by the manufacturer. A small clinical trial reported infants were exposed to 
ISSN:0146-4760
1945-2403
DOI:10.1093/jat/bkab055