A review of the antiviral activity of Chitosan, including patented applications and its potential use against COVID‐19

Chitosan is an abundant organic polysaccharide, which can be relatively easily obtained by chemical modification of animal or fungal source materials. Chitosan and its derivatives have been shown to exhibit direct antiviral activity, to be useful vaccine adjuvants and to have potential anti‐SARS‐CoV...

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Bibliographic Details
Published in:Journal of Applied Microbiology 2022-01, Vol.132 (1), p.41-58
Main Authors: Jaber, Nisrein, Al‐Remawi, Mayyas, Al‐Akayleh, Faisal, Al‐Muhtaseb, Najah, Al‐Adham, Ibrahim S. I., Collier, Phillip J.
Format: Article
Language:English
Subjects:
adjuvant
Adjuvants
Adjuvants, Vaccine
Animals
antimicrobial
Antimicrobial agents
antiviral
Antiviral activity
Antiviral Agents - pharmacology
Chemical modification
Chitosan
Chitosan - pharmacology
coronavirus
COVID
COVID-19
Humans
nanoparticles
Polysaccharides
Review
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
vaccine
Vaccines
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Summary:Chitosan is an abundant organic polysaccharide, which can be relatively easily obtained by chemical modification of animal or fungal source materials. Chitosan and its derivatives have been shown to exhibit direct antiviral activity, to be useful vaccine adjuvants and to have potential anti‐SARS‐CoV‐2 activity. This thorough and timely review looks at the recent history of investigations into the role of chitosan and its derivatives as an antiviral agent and proposes a future application in the treatment of endemic SARS‐CoV‐2.
ISSN:1364-5072
1365-2672
1365-2672
DOI:10.1111/jam.15202