Motivated displacement assay distinguishes ALA neuron mutants from RIS neuron mutants during recovery from heat stress in Caenorhabditis elegans

The interneurons ALA and RIS both regulate stress induced sleep in C. elegans but their roles in awake animal movement has been reported to differ. We describe the development of a motivated mobility-based assay that distinguishes between animals mutant for ALA function and those mutant for RIS func...

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Bibliographic Details
Published in:microPublication biology 2021-01, Vol.2021
Main Authors: Chávez-Pérez, Carlos, Jafari, Niusha, Keenan, Brendan T, Raizen, David M, Rohacek, Alex M
Format: Article
Language:English
Subjects:
C. Elegans
Methods
New Finding
New Methods
Online Access:Get full text
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Description
Summary:The interneurons ALA and RIS both regulate stress induced sleep in C. elegans but their roles in awake animal movement has been reported to differ. We describe the development of a motivated mobility-based assay that distinguishes between animals mutant for ALA function and those mutant for RIS function.
ISSN:2578-9430
DOI:10.17912/micropub.biology.000468