Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

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Bibliographic Details
Published in:Leukemia 2021-10, Vol.35 (10), p.3017-3020
Main Authors: Jones, J. R., Barber, A., Le Bihan, Y-V, Weinhold, N., Ashby, C., Walker, B. A., Wardell, C. P., Wang, H., Kaiser, M. F., Jackson, G. H., Davies, F. E., Chopra, R., Morgan, G. J., Pawlyn, C.
Format: Article
Language:English
Subjects:
45/23
631/67/1990/804
692/699/1541/1990/804
Adaptor Proteins, Signal Transducing - genetics
Biomarkers, Tumor - genetics
Cancer Research
Cancer therapies
Critical Care Medicine
Drug resistance
Drug Resistance, Neoplasm
Genes
Hematology
Hospitals
Humans
Immunomodulating Agents - therapeutic use
Immunomodulation
Intensive
Internal Medicine
Letter
Leukemia
Medical research
Medicine
Medicine & Public Health
Multiple myeloma
Multiple Myeloma - drug therapy
Multiple Myeloma - genetics
Multiple Myeloma - pathology
Mutation
Oncology
Patients
Transcription factors
Ubiquitin-Protein Ligases - genetics
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ISSN:0887-6924
1476-5551
DOI:10.1038/s41375-021-01373-4