Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritis

Abstract Objectives To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods Children aged 2 to

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Bibliographic Details
Published in:Rheumatology (Oxford, England) England), 2021-10, Vol.60 (10), p.4495-4507
Main Authors: Ruperto, Nicolino, Brunner, Hermine I, Pacheco-Tena, César, Louw, Ingrid, Vega-Cornejo, Gabriel, Spindler, Alberto J, Kingsbury, Daniel J, Schmeling, Heinrike, Borzutzky, Arturo, Cuttica, Rubén, Inman, C J, Malievskiy, Victor, Scott, Christiaan, Keltsev, Vladimir, Terreri, Maria Teresa, Viola, Diego Oscar, Xavier, Ricardo M, Fernandes, Taciana A Pedrosa, Velázquez, María del Rocío Maldonado, Henrickson, Michael, Clark, Michael B, Bensley, Karen A, Li, Xiaoming, Lo, Kim Hung, Leu, Jocelyn H, Hsu, Chyi-Hung, Hsia, Elizabeth C, Xu, Zhenhua, Martini, Alberto, Lovell, Daniel J
Format: Article
Language:English
Subjects:
Administration, Intravenous
Adolescent
Antibodies, Monoclonal - administration & dosage
Antirheumatic Agents - administration & dosage
Arthritis - drug therapy
Arthritis, Juvenile - drug therapy
Child
Child, Preschool
Clinical Science
Female
Humans
Male
Treatment Outcome
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Description
Summary:Abstract Objectives To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods Children aged 2 to
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/keab021